Science
Mechanism of Action
SACCHAROMYCES/RICE LEES FERMENT LYSATE functions on multiple levels within the skin. As a humectant and natural moisturizing factor (NMF) component, it significantly attracts and retains moisture, boosting skin hydration. It fortifies the skin's natural protective barrier, acting as a conditioning agent. The ingredient stimulates cellular metabolism and energy production by enhancing oxygen uptake and increasing cell turnover by up to 25%, leading to improved regeneration, reduced fine lines, and refined texture. Its rich antioxidant profile neutralizes free radicals, safeguarding the skin from environmental stressors. Furthermore, it stimulates collagen production for improved elasticity and firmness, regulates excess sebum, and inhibits tyrosinase activity to brighten skin tone. It also possesses anti-inflammatory properties, effectively soothing irritation and reducing redness.
Research
Clinical Evidence
Medium confidence1-3%
Key findings
- 01 Demonstrated skin whitening activity in a human skin trial, notably increasing skin brightness after 3 weeks.
- 02 Recommended formulation ratio for enhancing skin barrier function and inhibiting melanin production, while enriching the skin with amino acids.
- 03 Reported as an active ingredient in cosmetic compositions, exhibiting skin inflammation relieving, moisturizing, and exfoliation effects.
- 04 A related ingredient, Saccharomyces Lysate Extract, boosted oxygen uptake in skin cells by up to 750% and increased cell turnover activity by up to 25%.
Transparency
Dusting Analysis
Efficacy has been clinically observed at concentrations as low as 0.01%, with recommended formulation ratios for significant benefits ranging from 1% to 3%. It is reported for active use in cosmetic compositions at up to 20%, indicating functional incorporation rather than minimal inclusion for label claims.
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel currently classifies this ingredient's safety status as having 'insufficient data,' as it falls under a broader ongoing assessment of 'Yeast-Derived Ingredients.' While a specific safety assessment for SACCHAROMYCES/RICE LEES FERMENT LYSATE is pending, it has been reported as an active ingredient in cosmetic compositions at concentrations up to 20%. A related ingredient, Saccharomyces Lysate Extract, has been documented for use at up to 0.067% in sensitive formulations like baby products. No explicit SCCS opinion or FDA status for this exact INCI name was found.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SACCHAROMYCES/RICE LEES FERMENT LYSATE is a valuable multi-functional ingredient, offering significant hydration, brightening, barrier support, and anti-aging benefits for all skin types, with a low risk of irritation.
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References
Sources
- nih.gov ↗
- koken-cosme.com ↗
- google.com ↗
- niance.com ↗
- alfa-chemistry.com ↗
- lesielle.com ↗
- sincereskincare.com ↗
- revivalabs.com ↗
- mdpi.com ↗
- ulprospector.com ↗
- cir-safety.org ↗
- ci.guide ↗
- nuebiome.com ↗
- joshrosebrook.com ↗
- researchgate.net ↗