Science
Mechanism of Action
The ferment filtrate is rich in enzymes, peptides, and polysaccharides, collectively improving skin hydration and cellular function. Saccharomyces Ferment Filtrate actively supplies essential nutrients and potent antioxidants, working to mitigate inflammation, stimulate natural collagen synthesis, and improve skin elasticity and texture, visibly reducing the appearance of fine lines and wrinkles. Concurrently, it strengthens the skin's inherent barrier function. The Prunus mume extract component contributes powerful antioxidant capabilities, safeguarding the skin from free radical damage, and is noted for its content of vitamins C and E. It also offers moisturizing and soothing properties, aids in balancing sebum production, and supports skin regeneration, diminishing signs of fatigue. Furthermore, Prunus mume seed extract provides protection against UV-induced skin aging by modulating SIRT1 and MMP-1 expression and inhibiting the generation of reactive oxygen species.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Saccharomyces Ferment Filtrate has been shown to improve overall skin health, significantly reduce inflammation, promote collagen production, and enhance skin elasticity and texture, contributing to a reduction in fine lines and wrinkles. It also strengthens the skin's natural barrier.
- 02 In a clinical study involving 12 participants, a related Saccharomyces Cerevisiae ferment demonstrated a reduction in histamine-induced skin inflammation.
- 03 Prunus mume extract exhibits robust antioxidant properties, neutralizing over 45% of free radical activity in vitro at a concentration of 1000 µg/mL.
- 04 Prunus mume ripened seed extract (PmRS) protected against UV-induced skin aging in animal models, increasing collagen levels and reducing skin thickness by regulating SIRT1 and MMP-1, while also preventing UVB-induced reactive oxygen species in cell cultures.
- 05 Prunus mume fruit extracts have shown a skin-whitening effect by inhibiting melanin production via the regulation of melanogenesis-associated protein expression.
- 06 Clinically, Prunus mume extract suppressed glycation reactions and the accumulation of Advanced Glycation End-products (AGEs) in the skin, leading to improved skin transparency.
Transparency
Dusting Analysis
Effective concentrations for leave-on applications range from 0.1% to 5%. Usage below the 0.1% threshold for claimed skin benefits may indicate 'dusting' unless specific, lower-dose efficacy data is provided for that particular application.
The Formula
Formulation
Stability
Fermentative ingredients are often formulated without traditional preservatives, as the beneficial microbes are preserved, and harmful bacteria are typically separated, contributing to their inherent stability.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has issued 'Insufficient Data Announcements' for many yeast-derived ingredients, including Saccharomyces Ferment Filtrate, indicating that data is currently inadequate for a definitive safety determination in cosmetic formulations. While Saccharomyces cerevisiae is generally recognized as safe (GRAS) by the FDA for food use, this status does not directly apply to this cosmetic ingredient. Overall irritancy is considered low, with no reported side effects for Saccharomyces Ferment Filtrate and no toxicity observed for Prunus mume seed extract. However, a patch test is recommended, and the possibility of irritation exists when combined with other potentially problematic ingredients.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This fermented complex offers a broad spectrum of valuable benefits, including anti-aging, antioxidant, hydrating, and barrier-supporting properties, though regulatory safety data for cosmetic use remains insufficient.
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