Science
Mechanism of Action
Operating as a potent natural antioxidant, this ingredient effectively combats free radicals, mitigating their role in premature skin aging. The specialized fermentation process transforms ginseng, enhancing the bioavailability and skin absorption of key compounds such as nourishing polysaccharides, peptides, vitamins, minerals, and amino acids. It actively promotes skin regeneration, stimulates the synthesis of collagen and hyaluronic acid, and reinforces the skin barrier while supporting a healthy skin microbiome. Additionally, it targets hyperpigmentation by reducing melanin synthesis and decreasing tyrosinase activity, helps regulate sebum production to alleviate acne, and provides anti-inflammatory benefits by reducing reactive oxygen species (ROS) levels.
Research
Clinical Evidence
Medium confidence0.1%-5%
Key findings
- 01 A related ingredient, Fermented Red Ginseng (FRG) at 10%, was evaluated as practically nonirritating in a primary skin irritation test. It notably reduced skin sensitization rates to 20% (with a mean irritation score of 0.2%) compared to 100% sensitization observed with non-fermented red ginseng (mean score 1.4%).
- 02 At a concentration of 0.01% (100 µg/mL), a related ingredient, Fermented Black Ginseng (FBG), demonstrated significant inhibition of tyrosinase and melanin production in IBMX-stimulated B16F10 cells, coupled with a reduction in tyrosinase, TYRP-1, and MITF mRNA expression.
- 03 In an in vitro study, related Fermented Black Ginseng (FBG) at 0.2% (2 mg/mL) exhibited a substantial 55.10% inhibition of elastase, demonstrating superior performance compared to both non-fermented black ginseng and white ginseng.
Transparency
Dusting Analysis
Based on available research, this multi-functional ingredient is not commonly 'dusted.' Its broad benefits are typically achieved at concentrations within recommended efficacious ranges.
The Formula
Formulation
Stability
Optimal stability is generally observed within a pH range of 3.5 to 6.5, with specific fermentation broths maintaining stability between pH 4.6 and 5.2. It is recommended to avoid temperatures exceeding 60°C to preserve the ingredient's integrity. For maximizing ginsenoside stability in related red ginseng extracts, a pH range of 6-8 is indicated.
Safety
Safety Profile
Direct safety assessment by CIR, SCCS, or FDA for SACCHAROMYCES/PANAX GINSENG FERMENT FILTRATE is not readily available. However, related fermented ginseng ingredients, such as Fermented Red Ginseng, have been classified as practically non-irritating at 10% and shown significantly reduced sensitization compared to unfermented forms. While unfermented Panax ginseng has anecdotal reports of irritation, the fermentation process typically enhances safety and skin tolerability. A patch test is advisable for individuals with exceptionally sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SACCHAROMYCES/PANAX GINSENG FERMENT FILTRATE is a highly valuable ingredient for precision skincare, offering broad benefits from antioxidant protection and anti-aging to deep hydration and improved skin tone, with a favorable safety profile.
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