Science
Mechanism of Action
This ingredient operates by stimulating oxygen consumption within skin cells, thereby enhancing cellular energy production and supporting natural regeneration and repair processes. It provides vital nutrients, antioxidants, and is enriched with human-like cytokines and growth factors such as Tissue Growth Factor Beta (TGFb), Interleukin 1a (IL-1a), and Epidermal Growth Factor (EGF), which collectively help diminish the appearance of fine lines and wrinkles, reduce redness, and promote skin elasticity by stimulating soluble elastin production. Furthermore, it aids in balancing the skin's microbiome, maintaining sebum levels, inhibiting tyrosinase for a brightening effect, and offers deep hydration through its natural moisturizing factors (NMFs).
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Supplier information indicates effective use in concentrations of 3-20% for anti-wrinkle, anti-aging, and moisturizing products, demonstrating broad compatibility with cosmetic ingredients.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Lysates generally perform optimally within a pH range of 5-6. However, as a ferment filtrate, it exhibits flexibility and tolerates broader pH ranges within water-based systems.
Conflicts
- Oxidizing agents (may reduce efficacy or induce skin irritation/allergies)
- Acidic substances (may lower pH, potentially affecting ingredient efficacy)
- Formulations containing high percentages of alcohol
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has determined that current data are insufficient to ascertain the safety of Saccharomyces Lysate Filtrate and 22 related yeast-derived ingredients for use in cosmetic formulations. A request for confirmatory dermal sensitization data and information on food use/GRAS status was issued in June 2023. Nevertheless, prior dermal and ocular irritation tests on a mixture containing 24.5% Saccharomyces Ferment Lysate Filtrate, along with cellular viability assays on 25% Saccharomyces Lysate Extract, reported no cytotoxicity or irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Saccharomyces Lysate Filtrate presents a broad spectrum of potential benefits for skin health, including hydration, anti-aging, and barrier support, though its comprehensive safety profile remains under review by regulatory bodies such as the CIR.
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