Science
Mechanism of Action
This extract functions by supplying crucial biological components, including natural moisturizing factors such as glycine and proline, which reinforce the skin's inherent barrier function. It achieves deep hydration through a dual action of drawing and retaining moisture, concurrently stimulating aquaporin 3 (AQP3) expression. Furthermore, it acts as a natural antioxidant to neutralize free radicals, exhibits soothing and anti-inflammatory effects, and promotes both collagen synthesis and improved skin elasticity. Polysaccharides, notably β-glucan, further strengthen the skin barrier by stimulating tight junction protein synthesis.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 Continuous application of a 5% concentration over four weeks resulted in an average 37.2% reduction in trans-epidermal water loss (TEWL) and a 62.5% increase in stratum corneum hydration, demonstrating significant skin barrier repair.
- 02 A cosmetic composition containing 0.5% Saccharomyces yeast fermentation filtrate (in a mixture with other extracts) showed excellent inhibitory effects on NO production, indicating potent anti-inflammatory properties.
- 03 Recommended for use in leave-on products, it improves overall skin health, moisturizes, refines texture, reduces fine lines and wrinkles, exhibits antioxidant properties, decreases inflammation, promotes collagen, and enhances elasticity.
Transparency
Dusting Analysis
Effective concentrations for this ingredient are well-documented in clinical studies, showcasing significant benefits at percentages such as 0.5% and 5%. These established efficacy thresholds suggest that the ingredient is typically incorporated at levels that yield tangible results, mitigating the risk of being included merely for label claims.
The Formula
Formulation
Stability
Optimal stability is observed within a pH range of 4.0 to 6.0, consistent with the growth requirements of Saccharomyces cerevisiae yeast typically utilized in fermentation processes.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Panel has issued an 'Insufficient Data Announcement' for a group of yeast-derived ingredients, including Saccharomyces Ferment Filtrate, requesting further sensitization data. However, other sources generally consider this ingredient safe for topical use, with a low risk of irritation or allergic reactions. Patch testing is recommended prior to widespread application. For leave-on cosmetic products, a maximum concentration of 5% is advised.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted fermented extract is a valuable addition to precision skincare formulations, offering broad benefits for hydration, barrier integrity, and age-defying skin enhancement with a low risk profile.
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