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SACCHAROMYCES/DEFATTED MEALWORM LARVA FERMENT EXTRACT FILTRATE.

Insufficient Data / ANTIOXIDANT

SACCHAROMYCES/DEFATTED MEALWORM LARVA FERMENT EXTRACT FILTRATE is an advanced bio-ferment, produced by culturing Saccharomyces cerevisiae on defatted mealworm larva extract. This innovative process enhances the raw material's inherent properties, yielding a filtrate rich in revitalizing compounds designed to boost the skin's antioxidant defenses.

Summary

Antioxidant

Science

Mechanism of Action

The fermentation process with Saccharomyces cerevisiae significantly amplifies the antioxidant capacity of defatted mealworm larva extract. This occurs through a marked increase in total polyphenol, flavonoid, and amino acid content (approximately an 18% increase in amino acids), which collectively enhance the extract's radical scavenging activity, electron-donating ability, and reducing power. The underlying defatted mealworm powder also contributes functional peptides and glucosamine derivatives, offering inherent antioxidant and potential anti-inflammatory benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.1%

Key findings

  1. 01 At 0.1% concentration, the fermented extract demonstrated a 65.25% enhanced electron-donating ability, alongside superior radical scavenging activity and reducing power when compared to its non-fermented counterpart. This indicates a substantial improvement in its antioxidant profile, corroborated by significantly higher total polyphenol and flavonoid contents, and an approximate 18% increase in total amino acids post-fermentation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific stability data for the ferment filtrate is not detailed, protein solubility of the raw defatted mealworm meal was observed to be significantly less at pH 7 compared to pH 12, suggesting that higher pH values may improve the solubility of its protein components within a formulation.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Panel has not specifically assessed the safety of this complex ingredient. For related yeast-derived ingredients like 'Saccharomyces Ferment Filtrate', CIR has issued an 'Insufficient Data Announcement,' requesting further dermal sensitization data and information on food use/GRAS status. The presence of the mealworm component in this specific ferment extract filtrate would likely necessitate additional, dedicated safety evaluation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While displaying promising enhanced antioxidant properties in a preliminary study, comprehensive safety data, particularly regarding dermal sensitization and the novel mealworm component, is currently insufficient for a definitive recommendation.

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