Science
Mechanism of Action
This ingredient operates through a synergistic dual mechanism. The Boswellia serrata gum component provides boswellic acids, particularly acetyl-11-keto-β-boswellic acid (AKBA), which are potent inhibitors of pro-inflammatory enzymes like 5-lipoxygenase (5-LO), thereby significantly reducing redness, irritation, and swelling. It also contributes to skin firmness and elasticity by inhibiting elastase, an enzyme responsible for collagen degradation, and by its anti-glycosaminoglycan (GAGase) activity, which helps protect the skin’s natural moisturizing factors. Furthermore, it offers antioxidant and antimicrobial properties, aiding in pore refinement. Concurrently, the Saccharomyces ferment enriches the skin with essential minerals, amino acids, beta-glucan, and vitamins, delivering deep moisturization and soothing effects. This ferment also stimulates cell regeneration, facilitating faster and smoother healing of scars, reducing the appearance of stretch marks, and promoting a more uniform skin tone by minimizing sunspots, age spots, and splotches. It is also beneficial for balancing oily and acne-prone skin, and supplies vital lipids to aged skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
There is no specific data available in the provided research to indicate if this ingredient is commonly dusted or to establish dusting thresholds.
The Formula
Formulation
Stability
The Boswellia serrata component, an oleo-gum-resin, comprises both volatile (terpenes) and nonvolatile (boswellic acids) molecules. The stability of herbal extracts can be compromised by exposure to heat, light, pH fluctuations, and oxygen. Formulations designed to enhance solubility and bioavailability, such as natural self-emulsifying reversible hybrid-hydrogels or complexation with phosphatidylcholine, can improve both the stability and efficacy of the ingredient.
Synergies
- The combination of Saccharomyces ferment and Boswellia serrata gum synergistically enhances the ingredient's moisturizing, anti-inflammatory, and regenerative capabilities.
Safety
Safety Profile
A specific safety assessment by CIR or SCCS for the combined SACCHAROMYCES/BOSWELLIA SERRATA GUM FERMENT EXTRACT is not explicitly provided. However, its individual components have been evaluated. Saccharomyces cerevisiae, a ferment component, is generally recognized as safe (GRAS) by the FDA. Boswellia serrata extract is considered safe and well-tolerated at recommended concentrations. In vitro cytotoxicity tests on human skin-derived cell lines suggest that Boswellia serrata gum resin exhibits moderate to low toxicity, and genotoxicity studies have indicated it is non-mutagenic and non-clastogenic.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted ingredient is valuable for its potent anti-inflammatory, antioxidant, and regenerative properties, making it suitable for a wide range of skin concerns despite limited specific clinical data for the combined extract.
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