Science
Mechanism of Action
This ingredient functions by providing the skin with vital nutrients, antioxidants, beta-glucan, amino acids, and vitamins. It actively supports the reduction of inflammatory responses, stimulates the synthesis of collagen, and encourages the proliferation of both normal human epidermal keratinocytes and dermal fibroblasts. These actions collectively lead to improved skin elasticity, refined texture, a reduction in the appearance of fine lines and wrinkles, and a fortified natural barrier function, enhancing moisture retention and defense against environmental aggressors. Its lactic acid content further contributes to its significant moisturizing capacity.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 In a four-week study, continuous application of a Saccharomyces boulardii fermented product filtrate led to an average 37.2% reduction in trans-epidermal water loss (TEWL) and a 62.5% increase in stratum corneum hydration.
- 02 Porcine placenta ferment filtrate demonstrated stimulation of normal human epidermal keratinocyte (NHEK) proliferation.
- 03 Equine placenta ferment filtrate was shown to stimulate the proliferation of normal human epidermal keratinocytes (NHEKs).
- 04 Placenta ferment filtrates successfully stimulated the proliferation of normal human dermal fibroblasts.
Transparency
Dusting Analysis
Clinical efficacy has been observed across a range of concentrations, from 0.125% to 5%, indicating that low concentrations can yield biological effects. The ingredient is utilized at meaningful percentages for its advertised benefits.
The Formula
Formulation
Stability
Specific optimal pH or stability notes were not provided in the research data.
Safety
Safety Profile
The ingredient is deemed 'safe as used' by a final CIR report dated June 04, 2024. Recommended concentrations for leave-on products range from 0.1% to 5%. Saccharomyces cerevisiae, a component yeast, is recognized as 'generally recognized as safe' (GRAS) by the FDA up to 5% in food. Yeast-derived ingredients face no restrictions within the European Union. A patch test is suggested prior to full application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ferment filtrate offers comprehensive benefits including significant hydration, barrier strengthening, and cellular rejuvenation, making it a valuable addition for a wide range of skin types seeking enhanced vitality and resilience.
Related
Similar Ingredients
Finding similar ingredients…