Science
Mechanism of Action
This fermented rice bran filtrate delivers a wealth of essential nutrients and antioxidants, effectively mitigating inflammation and stimulating collagen synthesis to enhance skin elasticity. It actively fortifies the skin's barrier function, boosts hydration, and refines skin texture, which in turn diminishes the appearance of fine lines and wrinkles. The fermentation process amplifies its antioxidant capacity through compounds like gallic, ascorbic, and ferulic acids. Mechanistically, it significantly upregulates the expression of key moisturizing and barrier proteins (Aquaporin 3, Filaggrin, Hyaluronan Synthase 1) and tight junction proteins (Claudin 1, Involucrin, Zonula Occludens-1). Furthermore, it encourages fibroblast proliferation, neutralizes reactive oxygen species, and inhibits tyrosinase activity for skin brightening, while also contributing to sebum regulation and a balanced skin microflora.
Research
Clinical Evidence
Medium confidence3%
Key findings
- 01 In an in vitro study, significantly increased Aquaporin 3 (AQP3) protein content by 71% and Filaggrin (FLG) protein expression by 51% in human keratinocytes, indicating enhanced hydration and barrier function.
- 02 An in vitro study demonstrated a significant increase of 28% in Aquaporin 3 (AQP3) protein content and 26% in Filaggrin (FLG) protein expression in human keratinocytes, supporting skin hydration and barrier integrity.
- 03 In vitro testing on HFF-1 cells showed a substantial 198% enhancement in collagen synthesis when combined with Sialic Acid, compared to using 0.5% Yeast/Rice Fermentation Filtrate alone.
- 04 Used in in-vivo tests on young adult females for potential whitening, moisturizing, and anti-oxidation benefits, though specific quantifiable improvements at this concentration were not detailed.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a ferment filtrate, its stability profile is likely dependent on pH and temperature. Specific optimal ranges are not extensively documented, but its beneficial compounds are typically water-soluble, suggesting good dispersion in aqueous formulations.
Synergies
- Sialic Acid (for enhanced collagen synthesis)
Safety
Safety Profile
The CIR Expert Panel generally considers many yeast-derived ingredients safe in cosmetic use, particularly those from species recognized as safe for food or with minimal dermal sensitization. While this specific ingredient wasn't individually reviewed, components like 'Saccharomyces Ferment Lysate Filtrate' showed minimal to non-irritating effects in in vitro ocular assays at concentrations up to 24.5%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional ferment filtrate significantly enhances skin hydration, barrier integrity, and collagen production, while offering antioxidant and brightening effects suitable for all skin types.
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