Science
Mechanism of Action
This complex ferment filtrate operates through sophisticated biological pathways. The Saccharomyces ferment component actively provides vital nutrients and powerful antioxidants, effectively reducing inflammation and stimulating collagen synthesis. This process refines skin texture and elasticity while diminishing the appearance of fine lines. Concurrently, the Artemisia Princeps extract, enhanced by fermentation, delivers potent anti-inflammatory and antioxidant benefits. It functions by upregulating critical antioxidant enzymes and key skin barrier proteins, notably filaggrin and loricrin, thereby fortifying the skin's protective barrier, mitigating sensitivity, and balancing its microflora against environmental stressors. The fermentation process inherently amplifies the bioavailability of these beneficial compounds, intensifying their antioxidant activity and promoting superior cellular regeneration and repair.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 In clinical evaluations, Saccharomyces Ferment Filtrate at concentrations ranging from 0.1% to 5% in leave-on products demonstrated significant improvements in overall skin health. These benefits included providing essential nutrients and antioxidants, reducing inflammation, promoting collagen production, and enhancing skin elasticity and texture. Furthermore, it reduced the appearance of fine lines and wrinkles, strengthened the skin's natural barrier function, and provided effective moisturization.
- 02 Studies on Artemisia Princeps Extract, at concentrations up to 0.03%, indicated it was non-cytotoxic to normal human epidermal keratinocytes. It notably upregulated antioxidant enzymes and key skin barrier proteins, such as filaggrin and loricrin, suggesting its efficacy in improving dry skin symptoms and repairing the skin barrier.
- 03 A separate investigation utilizing a 5% Saccharomyces boulardii fermented product filtrate, applied consistently over four weeks, resulted in an average reduction of trans-epidermal water loss (TEWL) by 37.2% and an increase in stratum corneum hydration by 62.5%. This quantitatively supports its effectiveness in repairing damaged skin barriers.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient is highly soluble in water. Fermented components, such as Saccharomyces Ferment Filtrate, exhibit enhanced stability due to the natural purification occurring during the fermentation process. Additionally, Artemisia Princeps extract contains bioactive constituents that contribute to its natural preservative properties, potentially extending the product's shelf life.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed the safety of Saccharomyces Ferment Filtrate for use in cosmetics, supported by robust data, its Generally Recognized As Safe (GRAS) status by the FDA for food applications, and a lack of adverse findings in various toxicological studies. While Saccharomyces Ferment Filtrate is generally recommended for use up to 5% in leave-on products (and up to 10% in rinse-off formulations), it is critical to note that Artemisia Princeps Extract, specifically, demonstrated decreased cell viability in normal human epidermal keratinocytes at concentrations exceeding 0.3%. Formulators should meticulously consider the concentration of the Artemisia component within the combined ferment filtrate to ensure optimal safety and efficacy.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This highly valuable fermented ingredient offers a powerful combination of barrier-strengthening, anti-aging, soothing, and antioxidant properties, making it an excellent choice for a wide spectrum of skin concerns and types.
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