Science
Mechanism of Action
SACCHAROMYCES/ACANTHOPANAX SESSILIFLORUS EXTRACT FERMENT FILTRATE works multifactorially to support skin health. The fermentation process enriches the extract with essential nutrients, a diverse array of antioxidants, and beneficial compounds like polysaccharides, including β-glucan, which can stimulate tight junction protein synthesis for improved skin barrier function. This action contributes to enhanced skin texture, elasticity, and a reduction in the appearance of fine lines and wrinkles. The ingredient helps to modulate inflammatory responses, promoting overall skin calm and comfort. Furthermore, the Acanthopanax sessiliflorus ferment filtrate specifically exhibits antimicrobial, humectant, and skin-protecting properties, while also demonstrating immune enhancement through increased nitric oxide production and the modulation of inflammatory cytokines via NF-κB and ERK MAPK signaling pathways. This comprehensive approach ensures deep moisturization and robust natural barrier reinforcement.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
As a ferment filtrate, this ingredient is a liquid extract, not a powdered substance, therefore the concept of 'dusting' at sub-efficacious percentages is not applicable.
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has issued multiple 'Insufficient Data Announcements' (IDA) for broader categories of yeast-derived ingredients, including Saccharomyces Ferment Filtrate. These IDAs specifically request confirmatory dermal sensitization data, information on food use/Generally Recognized As Safe (GRAS) status, or 28-day dermal toxicity data. The precise ingredient, SACCHAROMYCES/ACANTHOPANAX SESSILIFLORUS EXTRACT FERMENT FILTRATE, has not undergone a separate, final safety assessment by the CIR Expert Panel, leading to an 'unknown' sensitization risk.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient demonstrates promising multifaceted benefits for skin health, including barrier repair, hydration, and antioxidant protection, but currently has insufficient safety data from regulatory bodies like the CIR, warranting further research.
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