Science
Mechanism of Action
Saccharomyces, frequently presented as Saccharomyces Ferment Filtrate, functions through several key pathways. It acts as a robust antioxidant, neutralizing free radicals and mitigating premature aging. Rich in bioavailable minerals, amino acids (such as glycine and proline), beta-glucan, and vitamins, it effectively draws and locks moisture into the skin, significantly boosting hydration. The fermentation process refines yeast components, improving their penetration and efficacy. This ingredient enhances cellular respiration and metabolism, stimulating the synthesis of structural proteins like collagen and elastin for improved elasticity and wrinkle reduction. It fortifies the skin's natural barrier by promoting tight junction protein expression and increasing moisture retention. Furthermore, Saccharomyces possesses natural calming properties, reducing sensitivity and redness, while supporting skin balance. It also contributes to a brighter, more even skin tone by inhibiting tyrosinase activity and exhibits anti-inflammatory effects, potentially inhibiting the growth of certain skin microbiota.
Research
Clinical Evidence
High confidence0.01-5% for targeted benefits like brightening and barrier repair; up to 30% for gentle exfoliation and enhanced hydration.
Key findings
- 01 Significantly suppressed melanin generation and increased skin brightness after 3 and 6 weeks, with no reported skin irritation. (Saccharomyces cerevisiae by-product)
- 02 Continuous use of a spray containing Saccharomyces boulardii fermented product filtrate for four weeks resulted in an average reduction of trans-epidermal water loss (TEWL) by 37.2%, while stratum corneum hydration increased by 62.5%.
- 03 Improved skin barrier function by increasing the expression of tight junction proteins and reducing photoaging in a lotion containing Saccharomyces/rice ferment filtrate with sunscreen.
- 04 Reduced histamine-induced skin inflammation, decreasing time to maximum blood perfusion and increasing the speed of inflammation resolution (dried Saccharomyces Cerevisiae ferment).
- 05 Provided gentle exfoliation and lightweight hydration (Saccharomyces Ferment formulation).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Saccharomyces Ferment demonstrates stability up to 60°C. While optimal efficacy for anti-aging is observed in the pH range of 3.0-5.0 (or 4.0-5.0 for Saccharomyces Cerevisiae Extract), some variants may perform effectively up to pH 7.5, and even 9.5 for odor reduction applications, indicating broad pH tolerance depending on the specific product goal.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel, in their June 2024 Final Report, deemed 'Saccharomyces Ferment Filtrate' safe for cosmetic use when derived from a Saccharomyces species (e.g., Saccharomyces cerevisiae) with adequate dermal sensitization data and recognized safety status (GRAS/QPS). The U.S. FDA affirms Saccharomyces cerevisiae as Generally Recognized As Safe (GRAS) for food use. While generally considered safe with a low risk of irritation or allergic reactions, patch testing is recommended for individuals with known skin sensitivities.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Saccharomyces is a valuable, multifunctional fermented ingredient that effectively enhances skin hydration, barrier function, brightness, and elasticity with a low risk of irritation across all skin types.
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