Science
Mechanism of Action
This cell-signaling molecule binds to keratinocyte receptors, stimulating collagen and elastin synthesis for improved elasticity and firmness. It accelerates wound healing by enhancing cell proliferation and tissue repair.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Significantly improved fine lines, texture, pore size, and dyschromatic conditions.
- 02 Reduced inflammatory acne lesions by 33.5% over six weeks.
- 03 Increased skin moisture and elasticity, and decreased transepidermal water loss.
- 04 Effective in diabetic wound healing and managing senile purpura.
Transparency
Dusting Analysis
No data suggests common dusting practices or concerns for this ingredient.
The Formula
Formulation
Stability
Highly sensitive to pH, requiring adjustment of cream pH to 5-8 before addition. Microbial contamination can lead to decomposition and activity loss.
Conflicts
- Microbial contamination
Safety
Safety Profile
While authorized, generalized cosmetic use has unknown long-term risks. As a growth factor, potential for tumorigenesis with dysregulation exists, though it is considered mitogenic, not mutagenic.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A powerful cell-communicating peptide that significantly improves skin texture, reduces signs of aging, and supports wound healing, though long-term safety for growth factors requires ongoing evaluation.
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