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Moumoujus

S-MUSSEL HEXAPEPTIDE-1 SP.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

S-Mussel Hexapeptide-1 SP is a multi-functional peptide designed to support overall skin health. It acts as a humectant and emollient, while also signaling endogenous repair mechanisms. This ingredient is proposed to enhance skin regeneration, elasticity, and provide some protection against environmental stressors.

Summary

Humectant Skin Conditioning Emollient Antioxidant Supports Collagen Production Enhances Skin Elasticity Promotes Skin Regeneration Reduces Appearance of Wrinkles Supports UV Protection

Science

Mechanism of Action

S-Mussel Hexapeptide-1 SP primarily functions as a humectant, skin conditioning agent, and emollient. Drawing insights from related hexapeptides such as Acetyl Hexapeptide-1, its mechanism is believed to involve stimulating pigmentation and melanin production through interaction with the MC1R receptor, potentially offering protection against UV-induced cellular damage and inflammation. Additionally, this peptide is expected to activate the skin's intrinsic repair pathways, promoting cellular regeneration, strengthening the dermal matrix, and improving overall skin tone, elasticity, and hydration by potentially boosting collagen and elastin synthesis, along with cellular ATP.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

For optimal stability, this peptide should be formulated within a pH range of 5 to 7. Direct heat exceeding 40°C must be avoided during processing. For long-term storage of concentrated solutions, refrigeration at -20°C for up to one month or deep freezing at -80°C for six months is recommended, always in sealed, moisture-free containers. If prepared as a water-based stock, it should be diluted, then sterile-filtered through a 0.22 μm filter prior to final use.

Conflicts

  • Avoid heat above 40°C
  • Caution advised when combining with other ingredients, as safety parameters may change
  • Safety on damaged skin (e.g., after microneedling) is unknown

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No direct safety assessments from CIR, SCCS, or FDA are available for S-MUSSEL HEXAPEPTIDE-1 SP. Major beauty ingredient databases currently list this ingredient as unrated, indicating ongoing evaluation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While S-MUSSEL HEXAPEPTIDE-1 SP demonstrates promising theoretical mechanisms for skin regeneration and protection based on related peptides, the absence of specific clinical studies and a comprehensive safety review necessitates further research for a definitive efficacy and safety profile.

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