Science
Mechanism of Action
This potent ingredient modulates neuromuscular transmission by selectively blocking NaV 1.4 sodium channels, predominantly found in muscle tissues. This action interrupts the rapid electrical signals necessary for muscle contraction, generating a 'Botox-like' relaxing effect on facial muscles that significantly diminishes mimic wrinkles. Additionally, S-Mu-Conotoxin CnIIIC obstructs neuronal nicotinic acetylcholine receptors (nAChR), particularly the α3β2 subtype, further contributing to its muscle-relaxing properties.
Research
Clinical Evidence
High confidence3%
Transparency
Dusting Analysis
Information regarding the common practice of 'dusting' this specific ingredient in formulations is not available in the provided research data.
The Formula
Formulation
Safety
Safety Profile
Exhibiting high dermatological safety, this ingredient is hypoallergenic, non-irritating, and non-sensitizing, with no reported side effects, making it suitable for sensitive skin. SkinSAFE rigorously classifies S-Mu-Conotoxin CnIIIc Acetate as '100 Free' from common allergy-causing ingredients, including fragrance, parabens, gluten, soy, and dyes, and is deemed safe for sensitive areas like eyelids, and for baby and teen use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
S-Mu-Conotoxin CnIIIC is a valuable biomimetic peptide delivering rapid and sustained muscle-relaxing, anti-wrinkle, and lifting effects with an exceptional safety profile suitable for all skin types.
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