Science
Mechanism of Action
This precision ingredient functions by binding with high affinity and specificity to target molecules, most notably ascorbic acid (Vitamin C). By forming a stable complex, S-DNA APTAMER-1 safeguards Vitamin C from oxidation, thereby preserving its activity and maximizing its skin benefits. This stabilization contributes to enhanced anti-inflammatory and moisturizing effects. As a class, aptamers offer superior advantages over traditional biomolecules, including smaller size, streamlined synthesis, inherent stability, and minimal immunogenicity, allowing for highly targeted interaction within skin formulations.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a DNA aptamer, S-DNA APTAMER-1 exhibits robust stability across various conditions, maintaining stable binding affinity within a pH range of 5 to 7. Synthetic oligonucleotides like aptamers can be stored long-term (over two years) at -20°C in a neutral buffer, and remain stable for over six weeks even at 37°C. Its intrinsic buffering capacity further aids in maintaining formula pH integrity.
Synergies
- Vitamin C (Ascorbic Acid)
Safety
Safety Profile
Regulatory assessments for S-DNA APTAMER-1 are not extensively documented by bodies like CIR or FDA. However, aptamers generally exhibit low toxicity and immunogenicity. Clinical observations of related DNA aptamers, such as 'Aptamin C' (s-DNA Aptamer-2) in complex with Vitamin C, have shown no toxicity or adverse reactions on human skin, even leading to improved skin irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
S-DNA APTAMER-1 is a valuable ingredient, particularly for enhancing the stability and effectiveness of sensitive actives like Vitamin C, leveraging its antioxidant and buffering properties for comprehensive skin benefits.
Related
Similar Ingredients
Finding similar ingredients…