Science
Mechanism of Action
S-CENTIPEDE OLIGOPEPTIDE-1 AMIDE functions as a signaling peptide, stimulating the body's natural processes for skin repair. Beyond this, it offers benefits as a skin conditioning agent, providing protection while also exhibiting antimicrobial properties.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Oligopeptide-1 and its variants, such as sh-Oligopeptide-1 (EGF), are highly susceptible to pH fluctuations and enzymatic degradation by microorganisms, which can lead to a loss of activity. To ensure stability, the pH of any formulation containing this peptide should be precisely adjusted to between 5.0 and 8.0 prior to its incorporation.
Safety
Safety Profile
A specific safety review by CIR, SCCS, or FDA for S-CENTIPEDE OLIGOPEPTIDE-1 AMIDE is not available. While the related compound sh-oligopeptide-1 (EGF) is authorized for cosmetic use at various concentrations, its long-term safety profile remains undefined. Furthermore, the scientific validity of some clinical studies on sh-oligopeptide-1 in cosmetics is often questioned, and its preclinical bioactivity has not been conclusively established.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While S-CENTIPEDE OLIGOPEPTIDE-1 AMIDE presents theoretical benefits for skin protection and conditioning, a lack of specific safety and efficacy data for this particular compound warrants a cautious approach.
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