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Moumoujus

RUBUS SUAVISSIMUS LEAF EXTRACT.

Valuable / SKIN CONDITIONING

Rubus Suavissimus Leaf Extract is a botanical active renowned for its potent antioxidant and anti-inflammatory properties, derived from the leaves of the sweet tea raspberry plant. Rich in bioactive compounds such as gallic acid, ellagic acid, and rubusoside, it targets inflammation and oxidative stress at a cellular level, promoting skin equilibrium.

Summary

Antioxidant Anti-inflammatory Skin-soothing Barrier support

Science

Mechanism of Action

This extract functions by modulating the skin's inflammatory response, primarily through suppressing proinflammatory cytokines like TNF-α, IL-6, and MCP-1, while simultaneously promoting beneficial anti-inflammatory adiponectin. Its rich profile of gallic acid, ellagic acid, rutin, and rubusoside further contributes to neutralizing free radicals, thereby mitigating oxidative damage and supporting overall cellular health.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a C57BL/6J mouse model, oral supplementation with Rubus suavissimus leaf extract at 0.1%, 0.5%, and 1.0% (w/v) effectively attenuated OVA-induced allergic responses. This was achieved by modulating immune desensitization, reducing IL-4, and increasing IL-10, IL-12a, and INF-γ. The extract also demonstrated efficacy in preserving intestinal barrier integrity and suppressing key proinflammatory cytokines (TNF-α, IL-6, MCP-1), while restoring anti-inflammatory adiponectin.

Transparency

Dusting Analysis

Not commonly dusted

No data suggests this ingredient is commonly used at sub-efficacious concentrations for marketing claims alone.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Exhibits excellent water solubility and stability, ensuring easy integration into various aqueous cosmetic formulations. Purification via alcohol precipitation is possible to remove non-active polysaccharides.

Conflicts

  • May potentially cause irritation for individuals with very sensitive skin due to its natural tannin content, by analogy with other species within the Rubus genus.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific safety review. EWG Skin Deep rates the extract with 'LOW' concerns for cancer, allergies/immunotoxicity, and developmental/reproductive toxicity. However, it's noted that EWG VERIFIED products require specific substantiation for its inclusion, and sensitive individuals may experience irritation due to tannins.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Rubus Suavissimus Leaf Extract is a valuable botanical with promising anti-inflammatory and antioxidant potential, though direct topical human clinical data would further solidify its efficacy in precision skincare.

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