Science
Mechanism of Action
This extract contains a powerful blend of beneficial compounds, including rosmarinic acid, flavonoids, phenolic acids, and diterpenes such as carnosic acid and carnosol. These components work synergistically to provide potent antioxidant protection, effectively neutralizing free radicals and shielding skin from environmental damage that leads to premature aging. Its anti-inflammatory action, primarily driven by carnosic acid and carnosol, helps downregulate inflammation-associated genes like IL-1β and TNF-α, calming irritated skin and reducing redness. Furthermore, it exhibits antimicrobial properties against a range of bacteria, supporting a clearer complexion. The extract also contributes to skin tautness and elasticity by protecting collagen and elastin, offers toning and astringent benefits, and may assist in regulating sebum production and supporting skin regeneration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Inhibited the growth of Staphylococcus aureus (gram-positive bacteria) at a concentration of 160 ul/ml.
- 02 Inhibited the growth of E. coli (gram-negative bacteria) at a concentration of 320 ul/ml.
- 03 Inhibited the growth of Salmonella typhi (gram-negative bacteria) at a concentration of 640 ul/ml.
Transparency
Dusting Analysis
Specific dusting thresholds for Rosmarinus Officinalis Callus Extract are not explicitly defined in the available data for topical application percentages. However, for the related Rosmarinus Officinalis Leaf Extract, formulations containing up to 0.2% were found to be non-irritating or non-sensitizing in clinical testing. While broader extracts can be used up to 5%, caution with patch testing is generally advised for sensitive individuals, suggesting a potential for irritation at higher concentrations depending on overall formulation.
The Formula
Formulation
Stability
Expected to be water-soluble, similar to other rosemary extracts, due to its polar active components like rosmarinic acid. The optimal pH range, referenced from related Rosmarinus Officinalis Leaf Extract, is 4.5-6.5, within which it can also function as a natural preservative.
Safety
Safety Profile
The CIR Expert Panel assessed Rosmarinus officinalis-derived ingredients, including the related Rosmarinus Officinalis (Rosemary) Leaf Extract, concluding safety in cosmetics when formulated to be non-sensitizing. For leave-on products, the leaf extract is safe at concentrations ≤0.2%. Rosmarinus Officinalis Callus Extract itself was not explicitly identified in this specific CIR review. While generally well-tolerated, its aromatic components can cause sensitivity in some individuals; therefore, a patch test is recommended prior to full usage for those with sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rosmarinus Officinalis Callus Extract is a valuable, multi-functional ingredient providing potent antioxidant, anti-inflammatory, and antimicrobial benefits, making it highly effective for diverse skin concerns, especially for maintaining a clear and healthy complexion.
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