Science
Mechanism of Action
While the precise mechanism of ROSMARINOYL TETRAPEPTIDE-75 has not been directly elucidated, its structure suggests a synergistic effect. Rosmarinic acid, a known antioxidant, typically protects skin keratinocytes from oxidative stress and prevents particulate matter-induced apoptosis. The tetrapeptide component, similar to Palmitoyl Tetrapeptide-7, is likely a signaling peptide that can stimulate the synthesis of crucial extracellular matrix proteins, such as collagen and fibronectin, thereby supporting skin structure. Additionally, tetrapeptides often exhibit anti-inflammatory capabilities by potentially inhibiting specific interleukins.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
There is no available data to suggest that ROSMARINOYL TETRAPEPTIDE-75 is a commonly 'dusted' ingredient, nor are there established dusting thresholds or red-flag percentages for its use, given its novel status.
The Formula
Formulation
Stability
Specific stability data for ROSMARINOYL TETRAPEPTIDE-75 is unavailable. However, related compounds like rosmarinic acid have shown stability in various liquid matrices, including acetate buffer at pH 5.5 and artificial gastric juice at pH 1.5, which may offer preliminary insights into potential stability considerations for the rosmarinoyl moiety.
Safety
Safety Profile
ROSMARINOYL TETRAPEPTIDE-75 has not undergone specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA. Its individual components, rosmarinic acid and Tetrapeptide-7 (Palmitoyl Tetrapeptide-7), are generally recognized ingredients in cosmetics, with rosmarinic acid being included in CIR assessments for rosemary-derived ingredients, and Tetrapeptide-7 having CosIng information as a skin conditioning agent. However, the safety profile of their combined form requires dedicated evaluation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
As a novel ingredient, ROSMARINOYL TETRAPEPTIDE-75 requires dedicated research to establish its precise efficacy, safety profile, and optimal formulation parameters before a definitive verdict can be rendered.
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References
Sources