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Moumoujus

ROSE KETONE-3.

Avoid CAS 57378-68-4 / PERFUMING

Rose Ketone-3 is a synthetic aromatic compound primarily incorporated into skincare and cosmetic formulations for its distinct fragrance properties. Despite its pleasant scent, it is recognized as a significant contact allergen, necessitating careful consideration of its inclusion.

Summary

Perfuming

Science

Mechanism of Action

This ingredient functions by imparting a pleasant aroma to cosmetic products and can also perfume the skin. Its action is limited to scent enhancement, without providing direct dermatological benefits.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

As a fragrance ingredient, Rose Ketone-3 is not typically 'dusted' in formulations to imply efficacy at sub-therapeutic levels. Its presence is solely for olfactive purposes.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The trans-isomer of Rose Ketone-3 exhibits robust stability, with a hydrolysis half-life extending to 332 days.

Conflicts

  • Potential to induce irritation and sensitization, particularly in individuals with predisposed skin sensitivities.
  • Increased risk of adverse reactions when co-formulated with other ingredients known for their irritant potential.
  • Strict adherence to maximum concentration limits is mandated due to its allergenic properties.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.011%
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not conducted an explicit standalone review for Rose Ketone-3. However, it is unequivocally identified as an established contact allergen in humans by the European Commission's Scientific Committee on Consumer Safety (SCCS). Its use in cosmetics is regulated under Annex III of the EC Cosmetics Regulation, indicating specific restrictions. While the US FDA considers it generally recognized as safe (GRAS) for food additive use, IFRA Standards restrict its maximum concentration in leave-on face products to 0.011% (Category 5A) due to its allergenic potential.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Rose Ketone-3 is a potent fragrance ingredient with no demonstrated skincare benefits and a high risk of sensitization and irritation, making it unsuitable for precision skincare formulations.

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