Science
Mechanism of Action
Rosa Rugosa Leaf Extract operates primarily as a potent antioxidant, effectively neutralizing free radicals and mitigating oxidative stress. It also exhibits anti-inflammatory effects, which can calm skin redness and swelling. Furthermore, it supports skin barrier function by promoting keratinocyte differentiation and increasing the expression of crucial proteins such as filaggrin (FLG), involucrin (IVL), loricrin (LOR), and claudin1 (CLDN1). These actions collectively contribute to improved skin hydration, texture, radiance, and overall anti-aging protection.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 In vitro studies have demonstrated a dose-dependent antioxidant capacity, with 5 mg/ml of extract achieving 45% activity, increasing to 60% at 10 mg/ml, and reaching 82% at 50 mg/ml against DPPH and ABTS free radicals. Notably, no cytotoxicity was observed in human keratinocytes up to 10 μg/ml.
- 02 Extracts from dried leaves harvested during fruiting, prepared in 70% v/v ethanol or methanol, have shown robust antioxidant activity, achieving up to 90% radical scavenging.
- 03 The extract has been shown to enhance skin barrier function by promoting keratinocyte differentiation and boosting the expression of key barrier proteins: filaggrin (FLG), involucrin (IVL), loricrin (LOR), and claudin1 (CLDN1).
Transparency
Dusting Analysis
The provided data does not indicate that Rosa Rugosa Leaf Extract is commonly 'dusted' in cosmetic formulations. The stability notes refer to the physical properties of the dry extract (hygroscopic, poor fluidity, high compressibility) which are manufacturing considerations for solid dosage forms, rather than consumer product efficacy.
The Formula
Formulation
Stability
The dry extract of Rosa Rugosa leaves is highly hygroscopic, prone to absorbing moisture from the environment. It exhibits suboptimal volumetric characteristics, poor fluidity, and a high compressibility coefficient, necessitating the use of auxiliary substances to improve flowability and compressibility, particularly in solid dosage forms.
Safety
Safety Profile
While specific CIR, SCCS, or FDA safety assessments for Rosa Rugosa Leaf Extract are not yet available, closely related ingredients such as Rosa damascena and Rosa canina extracts have been reviewed and deemed safe under certain use conditions. Independent evaluations by EWG Skin Deep and SkinSAFE platforms indicate a 'LOW' concern for potential issues including cancer, allergies & immunotoxicity, and developmental & reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rosa Rugosa Leaf Extract is a valuable ingredient, demonstrating potent antioxidant and anti-inflammatory properties while strengthening the skin barrier and providing hydration for enhanced skin texture and radiance.
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