Science
Mechanism of Action
This ingredient operates through several precise mechanisms: it robustly scavenges free radicals via its rich content of vitamin C, flavonoids, and polyphenols, thereby protecting against environmental damage. Its anti-inflammatory action is evidenced by a 43.2% reduction in PGE2 levels in LPS-stimulated macrophages and inhibition of TNF-α-induced reactive oxygen species (ROS) in dermal fibroblasts. Furthermore, it contributes to anti-aging by protecting collagen via reduced MMP-1 secretion and upregulated procollagen type I α1 expression. It also fortifies the skin barrier by promoting keratinocyte differentiation and increasing key components like FLG, IVL, LOR, and CLDN1, while offering hydrating, potential skin brightening, and mild astringent benefits.
Research
Clinical Evidence
High confidence0.01%
Key findings
- 01 Rosa rugosa flower extract powder at 0.01% (100 μg/mL) significantly decreased PGE2 levels by 43.2% in LPS-stimulated RAW 264.7 macrophage cells, demonstrating a notable anti-inflammatory effect.
- 02 Isolated rosarugosides A and D, constituents of Rosa rugosa, significantly reduced reactive oxygen species production in TNF-α-induced human dermal fibroblasts, indicating robust antioxidant and anti-aging benefits.
Transparency
Dusting Analysis
Clinical data supports significant anti-inflammatory effects at a specific concentration of 0.01% of the extract powder. This suggests a targeted therapeutic application rather than its inclusion merely for superficial marketing claims, distinguishing it from typically dusted ingredients.
The Formula
Formulation
Safety
Safety Profile
Rosa rugosa flower extract powder at concentrations up to 0.01% (100 μg/mL) did not compromise the viability of RAW 264.7 cells. Its isolated compounds were non-toxic to normal human dermal fibroblasts at concentrations below 100 µM. It is broadly considered safe for human keratinocytes and gentle on sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rosa Rugosa Flower Powder is a valuable ingredient, offering comprehensive antioxidant, anti-inflammatory, and anti-aging benefits with demonstrated efficacy at precise concentrations and high skin compatibility.
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