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Moumoujus

ROSA DAMASCENA CALLUS CULTURE CONDITIONED MEDIA.

Essential / ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

ROSA DAMASCENA CALLUS CULTURE CONDITIONED MEDIA is a regenerative botanical extract derived from rose stem cells, rich in bioactive components. It is precisely engineered to combat visible signs of aging, enhance skin vitality, and promote a more uniform, luminous complexion through its multi-faceted biological actions.

Summary

antioxidant moisturizer/humectant skin protecting anti-aging anti-inflammatory brightening skin regeneration collagen booster elastase inhibitor melanin inhibitor wound healing support skin soothing

Science

Mechanism of Action

This advanced ingredient operates through several synergistic pathways. It actively promotes skin regeneration and enhances cellular vitality to visibly diminish fine lines and wrinkles while improving hydration and elasticity. Its potent anti-inflammatory and antioxidant properties contribute to reducing acne, brightening skin, fading pigmentation, and providing defense against environmental pollutants. Key active components, including flavonoids, polyphenols, and polysaccharides, provide direct antioxidant, anti-inflammatory, and anti-wrinkle effects by inhibiting elastase activity and reducing melanin production. Furthermore, specific components like exosomes within the conditioned media significantly boost fibroblast proliferation, increasing collagen production by 40-120%, enhance cellular migration capacity by over 20% compared to controls, and modulate inflammatory responses by decreasing pro-inflammatory cytokines such as IL-6 by 50-60%. It also influences melanogenesis and extracellular matrix remodeling for overall skin health.

Research

Clinical Evidence

High confidence
Effective range 0.05–0.5%
Optimal

N/A

Key findings

  1. 01 Inhibition of elastase, contributing to anti-wrinkle and tightening effects, and significant reduction in melanin content for a prominent whitening effect.
  2. 02 Dose-dependent anti-inflammatory effects through 50-60% reduction in IL-6 in stimulated macrophages, enhanced fibroblast proliferation leading to 40-120% increased collagen production, and over 20% improvement in cellular migration capacity.

Transparency

Dusting Analysis

Not commonly dusted

This ingredient is a conditioned media, typically a liquid extract, and not commonly available in powdered form that would be subject to dusting concerns.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Panel has concluded that Rosa damascena-derived ingredients, including callus culture conditioned media, are safe for use in cosmetic practices at described concentrations, provided formulations are non-sensitizing. Rosa damascena Callus Extracellular Vesicles, a component, is registered with the Personal Care Products Council (PCPC). Related ingredients like Rosa damascena flower oil have shown no dermal irritation or phototoxic effects in animal studies or human patch tests.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Essential

With its scientifically supported multi-functional benefits spanning anti-aging, brightening, soothing, and regenerative properties, this ingredient is an essential component for advanced skin vitality and complexion enhancement.

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