Science
Mechanism of Action
The extract exhibits a broad spectrum of in vitro activities, including 100.0% anti-hyaluronidase, 92.7% antioxidant, 60.75% anti-elastase, 59.17% anti-inflammatory, and 30.28% anti-collagenase properties. These actions collectively contribute to preserving the skin's natural hyaluronic acid, neutralizing free radicals, protecting elastin and collagen from degradation, and mitigating inflammatory responses. This multi-targeted approach aids in skin repair and offers protection against damage from pollution and blue light.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An in vitro study utilizing a hydroalcoholic extract (3.1% yield from a 1/5 w/w stem/solvent ratio) demonstrated robust activity, achieving 100.0% anti-hyaluronidase, 92.7% antioxidant, 60.75% anti-elastase, 59.17% anti-inflammatory, and 30.28% anti-collagenase effects.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Obtained via hydroalcoholic extraction, this ingredient is soluble in both water and alcohol. While an optimal pH range for Rosa Centifolia Stem Extract is not specifically documented, a related Rosa Centifolia Flower Extract is stable between pH 4.0 and 7.0.
Conflicts
- Careful formulation is required to manage naturally occurring fragrance allergens like citronellol and geraniol to avoid sensitization.
- Adherence to Good Manufacturing Practices (cGMPs) is crucial to minimize the presence of potential impurities such as pesticide residues and heavy metals.
Safety
Safety Profile
The CIR Panel deemed it safe for cosmetic use when formulated to be non-sensitizing. A specific maximum concentration percentage was not stipulated, as its reported cosmetic use was limited in 2021 VCRP data. Concerns exist regarding naturally occurring fragrance allergens (citronellol, geraniol); formulators are advised to ensure levels do not cause sensitization. Rigorous good manufacturing practices (cGMPs) are essential to address potential impurities such as pesticide residues and heavy metals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rosa Centifolia Stem Extract is a valuable ingredient, demonstrating potent in vitro multi-functional benefits for anti-aging and environmental protection. Its safe integration into formulations necessitates careful management of naturally occurring allergens.
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References
Sources