Science
Mechanism of Action
Rosa Centifolia Leaf Cell Extract functions primarily as a powerful antioxidant, actively inhibiting oxygen-driven reactions and neutralizing unstable oxygen molecules responsible for cellular aging and free radical damage. It acts as an effective humectant, drawing and retaining vital moisture within the epidermal layers to restore the skin's hydrolipidic film. Additionally, this extract possesses significant anti-inflammatory and soothing properties, which mitigate redness and calm irritated skin. Its plant cells are known to stimulate and augment epidermal stem cell functions, thereby promoting skin regeneration, strengthening the skin barrier, and enhancing overall skin radiance, while also encouraging the production of collagen and elastin to reduce the appearance of fine lines and wrinkles.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 An ethanolic extract of Rosa centifolia was demonstrated to be safe in human fibroblasts.
- 02 The ethanolic extract of Rosa centifolia significantly mitigated UVB-induced DNA damage in human fibroblasts.
- 03 A methanolic extract of Rosa centifolia exhibited a notable sun protection factor (SPF) of 32.602 ± 0.430.
- 04 A methanolic extract of Rosa centifolia displayed strong antioxidant activity through DPPH radical scavenging.
Transparency
Dusting Analysis
Current research does not indicate that Rosa Centifolia Leaf Cell Extract is commonly 'dusted' or utilized at ineffectual concentrations in cosmetic formulations.
The Formula
Formulation
Stability
For natural extracts, it is recommended to conduct specific studies on solubility, potential discoloration, odor retention, and general stability during formulation to ensure optimal product integrity. The ingredient is generally stable within its identified pH range.
Conflicts
- Formulation must ensure non-sensitization, specifically by monitoring and controlling the levels of natural fragrance components like citronellol and geraniol.
- Concentration should be carefully managed to prevent potential irritation, especially considering observed moderate cytotoxicity and genotoxicity at the highest assayed concentrations in vitro.
Safety
Safety Profile
The CIR Expert Panel concluded that Rosa centifolia-derived ingredients are safe in cosmetics when formulated to be non-sensitizing. Caution is advised due to natural fragrance allergens (citronellol, geraniol) which are major volatile components and require labeling if exceeding 0.001% in leave-on or 0.01% in rinse-off products per European Cosmetics Regulation. While the US FDA considers rose absolutes, buds, and flowers as GRAS for food, R. centifolia extract has shown moderate cytotoxicity and genotoxicity at its highest tested concentrations in human fibroblasts, necessitating careful formulation at appropriate levels.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rosa Centifolia Leaf Cell Extract is a valuable, multifunctional ingredient that offers significant antioxidant protection, hydration, soothing effects, and supports skin regeneration, making it suitable for a broad spectrum of skin types when precisely formulated to mitigate potential sensitization risks.
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References
Sources