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Moumoujus

RICE RH-POLYPEPTIDE-45.

Valuable / SKIN CONDITIONING, SKIN PROTECTING

RICE RH-POLYPEPTIDE-45 is a precision-engineered peptide derived from rice, meticulously designed to revitalize skin. It actively stimulates fibroblast proliferation and boosts collagen synthesis, leading to visibly smoother, more toned skin. This ingredient also provides robust antioxidant protection and contributes to a strengthened skin barrier.

Summary

Skin-Conditioning Skin-Protecting Anti-aging Anti-wrinkle Antioxidant Brightening Moisturizing Elasticity-Enhancing Collagen-Boosting Hyaluronic Acid Preservation Cell Renewal

Science

Mechanism of Action

This potent rice-derived peptide functions by signaling fibroblasts to proliferate, thereby significantly elevating cellular metabolism and improving collagen synthesis within the skin. This sophisticated action directly contributes to the visible reduction of wrinkles and enhances skin smoothness and tone. RICE RH-POLYPEPTIDE-45 generally confers moisturizing, skin-rejuvenating, and elasticity-enhancing properties, fortifying the skin barrier and promoting cell renewal for a more radiant complexion. Furthermore, related rice protein hydrolysates have demonstrated abilities to inhibit hyaluronidase, aiding in the maintenance of skin's hyaluronic acid content, and antityrosinase activity for potential melanin reduction. Its strong antioxidant capabilities protect the skin by scavenging free radicals.

Research

Clinical Evidence

Medium confidence
Effective range 2–5%
Optimal

2%

Key findings

  1. 01 Reduces appearance of dark circles and puffiness; promotes smoother, rejuvenated, regenerated skin.
  2. 02 Inhibits hyaluronidase activity in vitro, maintaining hyaluronic acid content and reducing wrinkles.
  3. 03 Inhibits tyrosinase activity in vitro, contributing to skin whitening and treating pigmentation disorders.
  4. 04 Demonstrated dose-dependent activity for scavenging DPPH and ABTS free radicals, indicating antioxidant properties.

Transparency

Dusting Analysis

Not commonly dusted

No specific data suggests RICE RH-POLYPEPTIDE-45 is commonly dusted. Its effective concentrations, as indicated by studies on related complexes, suggest it is used at levels expected to provide functional benefits.

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 8
0 7 14

Stability

RICE RH-POLYPEPTIDE-45 is stable within a pH range of 5.5 to 8.0. For optimal preservation of its active properties, it must be incorporated into formulations at temperatures strictly below 40°C (104°F).

Conflicts

  • Vitamin serums: Co-application with certain vitamin serums may lead to reduced efficacy for both ingredients. It is generally recommended to apply peptides in the morning and vitamin serums at night to maximize individual benefits.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The specific ingredient 'RICE RH-POLYPEPTIDE-45' has not been individually reviewed by the CIR Expert Panel. However, the CIR Panel concluded in 2017 that most plant-derived proteins and peptides are safe for cosmetic use. Rice protein peptides are broadly considered to possess a high safety profile, being natural food proteins with low antigenicity, suggesting a reduced risk of immediate hypersensitivity reactions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

RICE RH-POLYPEPTIDE-45 is a valuable, multifaceted ingredient, leveraging rice-derived biotechnology to offer comprehensive skin benefits including significant anti-aging effects, potent antioxidant protection, and robust barrier enhancement.

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