Science
Mechanism of Action
This extract operates primarily as a powerful antioxidant by actively scavenging reactive oxygen species (ROS) and reactive nitrogen species (RNS), thereby preventing pro-oxidant cellular damage and inhibiting fatty acid oxidation. Its components strategically localize on the cell membrane's exterior to neutralize free radicals. Furthermore, Rhus Typhina Leaf Extract demonstrates anti-inflammatory and antimicrobial efficacy, including against bacteria associated with acne. It can also influence biomembrane functionality and provides astringent effects, contributing to skin toning and excess oil reduction.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In cellular models, concentrations ranging from 25-100 µg/mL effectively protected erythrocyte membrane integrity against strong oxidants and restored reduced glutathione levels up to 85% of control values. This demonstrated a strong antiradical action towards synthetic radicals and reactive oxygen species.
- 02 A 30 µg/mL water-acetone extract demonstrated superior protection of erythrocyte proteins and lipids against oxidation compared to its isolated main component, suggesting synergistic action within the extract itself.
Transparency
Dusting Analysis
Given its proven multi-functional benefits including potent antioxidant, anti-inflammatory, and antimicrobial activities, Rhus Typhina Leaf Extract offers a robust profile unlikely to be merely 'dusted' for marketing claims. Its demonstrated efficacy suggests genuine utility in formulations.
The Formula
Formulation
Stability
The extract exhibits good solubility in polar solvents, with mentions of water-acetonic, methanolic, and hydroalcoholic forms.
Synergies
- Demonstrates synergistic antioxidant action with its own components.
Safety
Safety Profile
While the raw Rhus typhina plant contains sap that can cause dermatitis and pollen known to cause allergies, the processed extract itself has shown low toxicity (LD50 = 5600 mg/kg) and no in vitro toxicity to erythrocytes. No specific cosmetic safety assessments by CIR, SCCS, or FDA were found. Note that the FDA's listing of Rhus coriaria (a related species) as a safe source of Tannic acid for food components does not directly extend to Rhus typhina leaf extract in cosmetics.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rhus Typhina Leaf Extract is a valuable, multi-functional ingredient that provides significant antioxidant protection, soothes inflammation, and offers balancing benefits for a wide range of skin types.
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References
Sources