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Moumoujus

RHUS SEMIALATA LEAF EXTRACT.

Valuable CAS - / ANTIFOAMING, ANTIMICROBIAL, ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Rhus Semialata Leaf Extract is a multi-functional botanical ingredient highly regarded for its potent antioxidant, anti-aging, and soothing properties. Rich in phenolic compounds, it actively helps protect skin cells from oxidative stress while contributing to enhanced elasticity and a visible reduction in wrinkles.

Summary

Antimicrobial Antioxidant Astringent Skin-Conditioning Agent Antifoaming Hair Conditioning Emollient

Science

Mechanism of Action

This extract primarily functions through its robust antioxidant capacity, driven by phenolic compounds like gallic acid, which neutralize reactive oxygen species (ROS) and stabilize mitochondrial membrane potential, thereby protecting skin cells from oxidative damage. Furthermore, it actively inhibits elastase, an enzyme responsible for breaking down elastin, thus preserving skin's structural integrity and promoting a firmer, more youthful appearance. Additional benefits include demonstrated anti-inflammatory and antibacterial effects, contributing to a calmer, healthier complexion, alongside potential moisturizing and emollient qualities.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated 15.28% elastase inhibitory activity, which contributes to improved skin elasticity and wrinkle reduction.
  2. 02 Exhibited significant antioxidant activity by effectively scavenging DPPH radicals.
  3. 03 Showed potent antioxidant effects as measured by the ABTS assay.
  4. 04 No significant cytotoxicity was observed in human keratinocytes (HaCaT cells).
  5. 05 A slight decrease in human keratinocyte (HaCaT cells) viability was noted.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

While specific stability data for Rhus Semialata Leaf Extract is limited, related studies indicate that ethanol extracts from Rhus semialata seeds demonstrate good stability against heat, light, and varying pH levels compared to root extracts.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

This ingredient has not been formally reviewed by major safety bodies like CIR, SCCS, or FDA. In vitro studies indicated no significant cytotoxicity in human keratinocytes at 10 µg/mL, with only a slight decrease in cell viability at 20 µg/mL. However, general caution is sometimes advised regarding high concentrations of gallotannins, which are found in related Rhus species, due to potential toxicity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

With its multifaceted benefits including antioxidant protection, anti-aging elastase inhibition, and soothing properties, Rhus Semialata Leaf Extract is a valuable addition to formulations targeting comprehensive skin health and resilience.

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