Science
Mechanism of Action
This extract exhibits robust antioxidant activity by directly scavenging free radicals such as DPPH and hydrogen peroxide, and by stimulating the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and catalase (CAT). Its anti-inflammatory effects may stem from reducing nitric oxide (NO) production and inhibiting key inflammatory pathways, including NF-κB and AP-1. Additionally, it shows potential to inhibit tyrosinase, which could modulate melanin biosynthesis, and possesses antimicrobial characteristics.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
No specific optimal pH range for Rhus Javanica Fruit Extract stability in cosmetic formulations is currently available. While an optimal pH of 2.0 was reported for antioxidant *extraction* from a related species (sumac, Rhus typhina L.), this does not directly pertain to cosmetic formulation stability.
Safety
Safety Profile
There is no specific safety assessment for Rhus Javanica Fruit Extract in cosmetic applications from major regulatory bodies like CIR or SCCS. While references to EPA toxicology data exist, a summarized safety status for cosmetic use is not provided. The ingredient is explicitly not recommended for fragrance or flavor use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rhus Javanica Fruit Extract is a valuable botanical active, showcasing significant in vitro antioxidant and anti-inflammatory properties, though further in vivo human data is needed to fully establish its efficacy and safety profile in specific cosmetic concentrations.
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