Science
Mechanism of Action
This ferment filtrate functions by inhibiting cellular melanin content and suppressing the expression of key melanogenesis-related proteins, such as microphthalmia-associated transcription factor (MITF) and tyrosinase, through the MEK/ERK signaling pathway. Additionally, it reduces the expression and activity of MMP-1, strengthening the skin barrier and mitigating aging. It also promotes or restores Type 1 collagen expression, contributing to wrinkle reduction and overall skin rejuvenation.
Research
Clinical Evidence
Medium confidence10%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability is suggested within a physiological pH range, likely between 5.5 and 8.53, reflecting the optimal growth conditions and enzyme activity of the source organism Rhodopseudomonas sphaeroides.
Safety
Safety Profile
While no specific safety assessments by CIR, SCCS, or FDA have been found for Rhodopseudomonas Sphaeroides Ferment Filtrate, general 'ferment filtrate' ingredients have undergone CIR review. It exhibits low irritancy in available data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This innovative ferment filtrate is a valuable multifunctional ingredient, offering clinically demonstrated benefits for anti-aging, skin brightening, barrier strengthening, and soothing sensitive skin.
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References
Sources