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RHIZOPHORA MANGLE EXTRACT.

Valuable CAS 90106-19-7 / HAIR CONDITIONING, SKIN CONDITIONING

Rhizophora Mangle Extract is a potent botanical ingredient recognized for its robust wound healing capabilities. It acts as a powerful antioxidant and anti-inflammatory agent, actively promoting skin regeneration and bolstering dermal integrity. This extract also exhibits antibacterial properties and shows promise in anti-aging applications.

Antioxidant Anti-inflammatory Antibacterial Wound Healing Collagen Synthesis Enhancer Elastase Inhibitor Soothing

Science

Rhizophora Mangle Extract operates through multifaceted mechanisms to benefit the skin. Its potent antioxidant action involves scavenging free radicals, inhibiting lipid peroxidation, and elevating the activity of vital antioxidant enzymes such as glutathione peroxidase and superoxide dismutase. It demonstrates anti-inflammatory efficacy by diminishing inflammatory cell presence and aiding the restoration of prostaglandin E2 (PGE(2)) levels. Furthermore, it exhibits antibacterial properties. For tissue repair, it promotes wound healing via enhanced wound contraction, stimulated angiogenesis, fibroblast proliferation, increased collagen fiber density, and elevated hydroxyproline content. Mechanistically, it may also contribute to anti-aging by inhibiting elastase activity and fostering collagen synthesis. Additional findings suggest antimutagenic properties through interaction with metallic ions and facilitation of DNA repair processes.


Research

High confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

Tinctures exhibited good stability across pH 3-7, with leaf tinctures showing particular stability at pH 5. The extract's soluble components are generally noted for high polarity.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Animal studies revealed no toxicological signs. Human clinical trials reported no adverse effects following topical application for wound healing and oral aphthous ulcers. No cytotoxicity was observed in RAW 264.7 cells at tested concentrations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Rhizophora Mangle Extract is a valuable botanical ingredient, clinically demonstrated for its significant wound healing, anti-inflammatory, and antioxidant properties, showing promising potential for overall skin health and regeneration.


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