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RHIZOPHORA MANGLE CALLUS CULTURE EXTRACT.

Valuable / ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

RHIZOPHORA MANGLE CALLUS CULTURE EXTRACT is a precision botanical ingredient derived from mangrove callus cultures, recognized for its comprehensive benefits in skin vitality. It actively contributes to anti-aging by preserving skin structure, reducing inflammation, and providing antioxidant protection.

Summary

Antioxidant Anti-inflammatory Collagen Synthesis Booster Elastase Inhibitor Skin Conditioner

Science

Mechanism of Action

This extract operates through a multi-modal approach to enhance dermal health. It effectively inhibits elastase, an enzyme implicated in the degradation of elastin, thereby helping to maintain skin elasticity. Simultaneously, it stimulates the synthesis of new collagen, crucial for skin firmness. Furthermore, it exhibits potent anti-inflammatory properties and acts as a scavenger of free radicals, protecting cellular integrity against oxidative stress.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–10%
Optimal

N/A

Key findings

  1. 01 Clinical investigations (KR20130050173A) indicate efficacy within a concentration range of 0.1% to 10%, demonstrating inhibition of elastase, promotion of collagen synthesis, reduction of inflammation, and free radical scavenging. Concentrations below 0.1% are considered insignificant, while those above 10% may lead to safety and formulation stability issues.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest this ingredient is commonly 'dusted' or used at sub-efficacious concentrations by the industry; therefore, no specific dusting threshold or red flag percentage can be identified.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Formulation stability is a critical consideration; concentrations exceeding 10% by weight have been noted to potentially lead to stability challenges. Optimal pH for the extract's stability in formulations is not specified, though a pH range of 5.6-5.8 was noted for optimal callus *induction media*, which is distinct from formulation stability.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Unknown

While concentrations up to 10% are considered effective, exceeding this threshold may introduce safety concerns and compromise formulation stability. Comprehensive safety assessments by bodies such as CIR, SCCS, or FDA are currently unavailable for Rhizophora Mangle Callus Culture Extract.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Rhizophora Mangle Callus Culture Extract is a valuable, multi-functional ingredient offering significant anti-aging, anti-inflammatory, and antioxidant benefits within a clinically indicated concentration range, pending broader independent safety and formulation data.

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