Science
Mechanism of Action
This extract exerts its dermatological effects through several key mechanisms. It demonstrates strong antioxidant activity, effectively neutralizing free radicals to protect the skin from environmental damage and premature aging. Its anti-inflammatory benefits help to soothe irritation, reduce visible redness, and are particularly beneficial for sensitive skin, including conditions like rosacea and acne. The extract also stimulates skin regeneration by promoting cell renewal and enhancing the production of skin barrier lipids, potentially through compounds such as rhaponticin. Additionally, it offers subtle moisturizing properties, assists in regulating sebum secretion, refines pore appearance, and possesses antiseptic qualities to help prevent bacterial issues. Its photoprotective potential is evidenced by its ability to inhibit tyrosinase and tyrosine kinase activities, along with reducing inflammatory markers in UV-exposed melanocytes, suggesting roles in skin brightening and sun damage prevention.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A human clinical study showed that a cream containing 10.0-20.0% Rheum officinale stem extract significantly repaired damaged skin barriers and delayed senility after 28 days of use.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract is commercially obtained via solvent extraction, commonly using water or ethanol, followed by filtering, concentration, and drying. It has been successfully incorporated into cosmetic preparations at concentrations of 10.0-20.0% in water-based phases, often alongside glycerin, propylene glycol, sodium hyaluronate, and carbomer.
Safety
Safety Profile
A specific Cosmetic Ingredient Review (CIR) or SCCS safety assessment for dermal cosmetic use is not available. While general Rheum officinale extracts may cause hypersensitivity, the stem is distinct from leaves, which contain high oxalates. Dermal toxicity for this specific stem/root extract is currently undetermined.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Rheum Officinale Stem Extract is a valuable, multi-functional ingredient showing promising effects in skin barrier repair, anti-aging, and soothing, although comprehensive dermal safety assessments for cosmetic use are still pending.
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