Science
Mechanism of Action
This synthetic recombinant single-chain peptide mimics human Interleukin 10 (IL-10), a key anti-inflammatory cytokine, to regulate the immune response and antibody production. Acting as an anti-histamine and immunosuppressive agent, RH-POLYPEPTIDE-6 alleviates itching and burning, reduces scratching, and inhibits autoimmune reactions. Additionally, it downregulates collagen type I production, contributing to the prevention of scar tissue during wound healing.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical observations suggest RH-POLYPEPTPE-6 alleviates itching and burning sensations caused by allergens. It has shown efficacy in cases of psoriasis and in normalizing an overactive immune system that produces excess immune cells. Furthermore, it helps prevent scar tissue formation during wound healing and is indicated as a potential treatment for keloid scarring.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specific optimal pH for stability is not detailed for RH-POLYPEPTIDE-6, peptides generally exhibit pH-dependent stability and activity.
Safety
Safety Profile
RH-POLYPEPTIDE-6 is described as a safe, soothing ingredient for reactive or sensitive skin. Although the Cosmetic Ingredient Review (CIR) Expert Panel has assessed general categories of proteins and peptides as safe for cosmetic use, specific CIR or SCCS review data for RH-POLYPEPTIDE-6 is currently unavailable. The FDA does not pre-approve cosmetic ingredients.
Your Skin
Skin Compatibility
Our Assessment
Verdict
RH-POLYPEPTIDE-6 is a valuable ingredient due to its powerful anti-inflammatory and soothing properties, making it highly effective for calming irritated and reactive skin, and showing promise in scar prevention.
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References
Sources