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RH-POLYPEPTIDE-50.

Valuable / SKIN CONDITIONING

RH-POLYPEPTIDE-50 is a synthetic recombinant peptide designed to mimic tropoelastin, a crucial protein for maintaining skin's structure and elasticity. It actively works to reduce visible signs of aging by enhancing dermal resilience.

Skin-identical ingredient Cell-communicating ingredient

Science

This peptide penetrates the epidermis to stimulate fibroblasts, thereby boosting the production of collagen and other extracellular matrix proteins. This action leads to improved skin elasticity, firmness, and overall reduction in aging signs.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 56-day split-face study (n=46) demonstrated up to 45% reduction in wrinkle depth, volume, and surface area. A separate 42-day tolerance study (n=28) confirmed high compatibility and improvements in texture, hydration, and elasticity.

Transparency

Not commonly dusted

There is no information to suggest this ingredient is commonly dusted in cosmetic formulations.


The Formula

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

Peptides are pH-sensitive and require protection from stress; optimal stability is often within pH 3-7, with buffers at pH 3-5 beneficial. Store at 2-8°C, protected from light, and avoid freezing.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

CIR status is not reviewed. While generally considered safe for topical use, patch testing is recommended due to potential for irritation or allergic reactions in sensitive individuals.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

A valuable anti-aging peptide that promotes skin elasticity and firmness by stimulating collagen and elastin production, suitable for all skin types.


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