Science
Mechanism of Action
This synthetic recombinant human prolactin hormone analog peptide, comprising 199 amino acids, acts topically to bolster epidermal thickness and suppress inflammatory responses within the skin. It actively contributes to reducing the visual depth of fine lines and wrinkles, lessens melanin production for a more even complexion, and promotes robust skin regeneration, specifically aiding in the recovery from UV-induced damage.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 A manufacturer's clinical trial, conducted over 12 weeks with daily application of a 2% cream, demonstrated statistically significant reductions in wrinkle depth. The study also highlighted its effectiveness in repairing UV-damaged skin and contributing to skin brightening.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a peptide, RH-POLYPEPTIDE-28 may experience destabilization and reduced efficacy when exposed to highly acidic environments.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not published a specific safety assessment for RH-POLYPEPTIDE-28 (sh-Polypeptide-28). While the FDA does not 'approve' cosmetic ingredients, it mandates that they be safe for consumer use under intended conditions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
RH-POLYPEPTIDE-28 is a valuable peptide, demonstrating significant efficacy at a 2% concentration in addressing multiple signs of aging, promoting skin repair, and enhancing overall skin vitality.
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References
Sources