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RH-POLYPEPTIDE-28.

Valuable CAS - / REDUCING, SKIN CONDITIONING

RH-POLYPEPTIDE-28 is a sophisticated synthetic peptide engineered to stimulate skin regeneration and improve overall epidermal health. This advanced ingredient effectively diminishes the appearance of fine lines and wrinkles, brightens skin tone by reducing melanin, and aids in repairing UV-induced cellular damage.

Anti-aging Skin brightening UV damage repair Skin regeneration Anti-inflammatory Epidermal thickening Moisturizing support

Science

This synthetic recombinant human prolactin hormone analog peptide, comprising 199 amino acids, acts topically to bolster epidermal thickness and suppress inflammatory responses within the skin. It actively contributes to reducing the visual depth of fine lines and wrinkles, lessens melanin production for a more even complexion, and promotes robust skin regeneration, specifically aiding in the recovery from UV-induced damage.


Research

Medium confidence
Effective range 2–2%
Optimal

2%

Key findings

  1. 01 A manufacturer's clinical trial, conducted over 12 weeks with daily application of a 2% cream, demonstrated statistically significant reductions in wrinkle depth. The study also highlighted its effectiveness in repairing UV-damaged skin and contributing to skin brightening.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a peptide, RH-POLYPEPTIDE-28 may experience destabilization and reduced efficacy when exposed to highly acidic environments.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not published a specific safety assessment for RH-POLYPEPTIDE-28 (sh-Polypeptide-28). While the FDA does not 'approve' cosmetic ingredients, it mandates that they be safe for consumer use under intended conditions.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

RH-POLYPEPTIDE-28 is a valuable peptide, demonstrating significant efficacy at a 2% concentration in addressing multiple signs of aging, promoting skin repair, and enhancing overall skin vitality.


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