Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

RH-OLIGOPEPTIDE-2.

Valuable CAS - / SKIN PROTECTING

RH-Oligopeptide-2 is a synthetic, cell-communicating peptide that mimics natural growth factors, effectively signaling skin cells to regenerate and repair. This potent ingredient works to restore a youthful complexion by significantly improving skin elasticity, minimizing fine lines, and accelerating tissue repair.

Summary

Cell-communicating ingredient Skin conditioning Skin protecting Promotes skin regeneration Improves elasticity Reduces fine lines and wrinkles Hydrates skin Tones skin Accelerates wound healing Enhances collagen production Promotes hyaluronic acid synthesis Smooths skin texture Reduces blotchiness

Science

Mechanism of Action

Functioning as a signaling molecule, RH-Oligopeptide-2, also known as Insulin-like Growth Factor-1 (IGF-1), activates the cellular AKT pathway to promote cell proliferation and tissue repair. It selectively binds to receptors on skin cells, stimulating dermal fibroblasts to generate essential connective tissues and epidermal keratinocytes to accelerate their growth. This action concurrently boosts the biosynthesis of crucial extracellular matrix components, including collagen types I, III, and IV, elastin, fibronectin, and hyaluronic acid, thereby enhancing skin structure and hydration.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated RH-Oligopeptide-2. General caution is advised for any growth factor-mimicking peptide, as these are correlated with tumorigenesis or progression in some contexts. While the FDA has noted potential immunogenicity risks for certain compounded peptides, RH-Oligopeptide-2 is not explicitly listed among specific concerns in the provided data.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

RH-Oligopeptide-2 is a valuable ingredient for advanced skincare, offering significant regenerative and anti-aging benefits through its multifaceted cellular communication, although further independent safety evaluations would enhance its profile.

Related

Similar Ingredients

Finding similar ingredients…