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RESVERATROL DIMETHYL ETHER.

Valuable CAS 537-42-8 / ANTIOXIDANT, SKIN CONDITIONING

Also known as Pterostilbene, Resveratrol Dimethyl Ether is a potent derivative of resveratrol, engineered for enhanced stability and bioavailability. It acts as a powerful antioxidant, protecting skin from oxidative stress and inflammation while delivering comprehensive anti-aging benefits.

Antioxidant Anti-inflammatory Anti-aging Skin Brightening Skin Conditioning Barrier Support Wound Healing

Science

Resveratrol Dimethyl Ether primarily functions as an antioxidant, neutralizing reactive oxygen species and inhibiting oxygen-favored reactions to prevent oxidative damage and rancidity in the skin. It also exhibits anti-inflammatory properties and targets cellular senescence. Mechanistically, it activates the Nrf2/HO-1 signaling pathway to bolster antioxidant defenses, suppresses matrix metalloproteinase-1 (MMP-1) expression to mitigate collagen degradation, and downregulates tyrosinase and MITF to improve hyperpigmentation. Furthermore, it supports wound healing, stimulates the skin's natural collagen production, enhances firmness and elasticity, and contributes to barrier repair and protection.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 3 – 7
0 7 14

Stability

This ingredient maintains stability within a pH range of 3 to 7, with optimal conditions typically observed between pH 5 and 6. As a more stable derivative of resveratrol, it is designed to mitigate some of the stability challenges of its parent compound. However, it remains susceptible to photodegradation upon UV exposure and oxidation, necessitating protection from light and air. High pH environments (above 7) and strong oxidizing agents should be avoided to prevent degradation and potential discoloration.

Conflicts

  • strong oxidizing agents
  • high pH environments (above 7)

Safety

CIR Status
Not reviewed
Sensitization risk Low

While specific safety assessments by CIR or SCCS for Resveratrol Dimethyl Ether are not widely available, cosmetic ingredients in the EU are subject to rigorous safety regulations. Its parent compound, resveratrol, is generally recognized as safe for all skin types and considered non-irritating, with some minimal irritation noted at 0.5% concentrations. INCIDecoder ratings indicate low irritancy and comedogenicity for this derivative, suggesting a favorable safety profile for topical application.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This highly stable resveratrol derivative offers robust antioxidant and anti-inflammatory benefits, effectively targeting multiple signs of aging and improving overall skin health.


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