Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

RAPHANUS SATIVUS LEAF EXTRACT.

Valuable CAS 84775-94-0 / HUMECTANT

Raphanus Sativus Leaf Extract is a botanical ingredient derived from radish leaves, recognized for its comprehensive dermatological benefits. Rich in potent antioxidants, it actively combats environmental stressors, supports skin integrity, and offers multifaceted effects including hydration, soothing, and gentle purification. While many studies focus on related radish root or sprout extracts, the Cosmetic Ingredient Review (CIR) panel considers these components to share similar safety and efficacy profiles.

Antioxidant Anti-inflammatory Antimicrobial Hydrating Skin Conditioning Astringent Exfoliant (gentle) Skin Brightening (mild)

Science

Raphanus Sativus extracts function through several key mechanisms. They are abundant in antioxidant-rich phenolic compounds, including Vitamin C, polyphenols, anthocyanins, and flavonoids, which neutralize reactive oxygen species and mitigate oxidative stress induced by UV radiation and pollution. This protective action helps preserve collagen, reduce free-radical damage, and prevent premature aging, hyperpigmentation, and inflammation. The extract may also exert a mild inhibitory effect on tyrosinase, an enzyme involved in melanin synthesis, potentially contributing to a brighter complexion and the reduction of dark spots. Furthermore, its inherent antibacterial and antifungal properties can support a balanced skin microbiome, while anti-inflammatory components reduce redness and irritation. Organic acids within the extract facilitate gentle exfoliation, promoting cellular renewal, and its astringent qualities help balance sebum production, purify the skin, and refine pore appearance, concurrently enhancing skin hydration and fortifying the epidermal barrier.


Research

Medium confidence
Effective range 1–5%
Optimal

N/A

Key findings

  1. 01 Raphanus Sativus *root* extract has been utilized in skincare for its antioxidant capabilities and a mild, though low-potency, effect on tyrosinase inhibition.
  2. 02 Raphanus Sativus *sprout* extracts, when formulated into topical gels, demonstrated excellent physical stability and pH compatibility (4.5–5.5). These extracts are linked to antioxidant, antimicrobial, and anti-inflammatory benefits, along with improved skin hydration and barrier function.

Transparency

Not commonly dusted

No specific data suggests Raphanus Sativus Leaf Extract is commonly 'dusted' or used at concentrations below a functional threshold purely for marketing claims.


The Formula

Solubility
Both
Optimal pH 4 – 5.5
0 7 14

Stability

Raphanus Sativus *sprout* extracts exhibit good physical stability within topical gel formulations at pH levels ranging from 4.5 to 5.5. An ethyl acetate *root* extract has also shown stability at pH 4 and temperatures up to 70°C, indicating robustness across different radish extracts.

Conflicts

  • When formulating with multiple botanicals, formulators should be mindful of the cumulative levels of anthocyanins and isothiocyanates to prevent potentially hazardous concentrations.

Safety

CIR Status
Safe as used
Max tested
6%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Panel has deemed radish *root-derived* ingredients, which are considered related to leaf extract, safe for cosmetic use under current practices and concentrations, particularly when formulated to be non-sensitizing. This assessment is supported by the common consumption of radish roots as food. The highest reported maximum concentration for Raphanus Sativus Root Extract in leave-on products is up to 6% (specifically in lipstick). Adherence to current Good Manufacturing Practices (cGMPs) is crucial to minimize impurities such as pesticide residues and heavy metals. Studies involving fermented radish leaf and root extracts have indicated no cytotoxicity to skin cells.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Raphanus Sativus Leaf Extract is a valuable botanical offering broad-spectrum antioxidant defense, anti-inflammatory benefits, and skin-conditioning properties, suitable for all skin types and considered safe for use in diverse cosmetic formulations.


Related

Finding similar ingredients…