Science
Mechanism of Action
This ingredient functions as a potent signaling molecule, leveraging the combined actions of its core components, SH-Oligopeptide-1 (Epidermal Growth Factor, EGF) and SH-Polypeptide-1 (Basic Fibroblast Growth Factor, bFGF). EGF is renowned for stimulating keratinocyte proliferation, enhancing blood vessel formation, and promoting the secretion of factors vital for scar-free wound healing. It further contributes to strengthening the skin barrier and provides long-term hydration by boosting extracellular matrix components like collagen, elastin, and hyaluronic acid. Concurrently, bFGF specifically targets fibroblasts, encouraging their growth and proliferation, which is essential for the generation and repair of collagen and other vital extracellular matrix proteins.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) Expert Panel has deemed general categories of skin and connective tissue-derived proteins and peptides as safe for use, R-(SH-OLIGOPEPTIDE-75 SH-POLYPEPTIDE-1) itself has not undergone a specific CIR assessment. Related components, such as sh-oligopeptide-1, have noted 'unknown long-term risks' and a lack of proven preclinical bioactivity, suggesting the need for more specific safety data for this particular complex peptide.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Possessing a theoretically robust mechanism for skin regeneration and anti-aging through its growth factor components, this ingredient currently lacks specific clinical studies and comprehensive safety assessments to fully confirm its efficacy and long-term safety profile.
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