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R-(SH-OLIGOPEPTIDE-75 SH-POLYPEPTIDE-1).

Insufficient Data / ANTI-SEBUM, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

R-(SH-OLIGOPEPTIDE-75 SH-POLYPEPTIDE-1) is a sophisticated recombinant synthetic human peptide, engineered to mimic natural signaling molecules within the skin. It is designed to encourage fundamental cellular processes crucial for skin repair, renewal, and overall dermal health, potentially improving various signs of aging and damage.

Cell Proliferation Skin Renewal Wound Healing Scar Reduction Anti-inflammatory Skin Barrier Enhancement Moisturizing Collagen Synthesis Elastin Synthesis Hyaluronic Acid Synthesis Anti-aging Firming Elasticity Improvement Hyperpigmentation Management Scalp Conditioning Hair Strengthening

Science

This ingredient functions as a potent signaling molecule, leveraging the combined actions of its core components, SH-Oligopeptide-1 (Epidermal Growth Factor, EGF) and SH-Polypeptide-1 (Basic Fibroblast Growth Factor, bFGF). EGF is renowned for stimulating keratinocyte proliferation, enhancing blood vessel formation, and promoting the secretion of factors vital for scar-free wound healing. It further contributes to strengthening the skin barrier and provides long-term hydration by boosting extracellular matrix components like collagen, elastin, and hyaluronic acid. Concurrently, bFGF specifically targets fibroblasts, encouraging their growth and proliferation, which is essential for the generation and repair of collagen and other vital extracellular matrix proteins.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While the Cosmetic Ingredient Review (CIR) Expert Panel has deemed general categories of skin and connective tissue-derived proteins and peptides as safe for use, R-(SH-OLIGOPEPTIDE-75 SH-POLYPEPTIDE-1) itself has not undergone a specific CIR assessment. Related components, such as sh-oligopeptide-1, have noted 'unknown long-term risks' and a lack of proven preclinical bioactivity, suggesting the need for more specific safety data for this particular complex peptide.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Possessing a theoretically robust mechanism for skin regeneration and anti-aging through its growth factor components, this ingredient currently lacks specific clinical studies and comprehensive safety assessments to fully confirm its efficacy and long-term safety profile.


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