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Moumoujus

R-(S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-62).

Questionable / ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

This advanced ingredient is a complex of sr-rainbow trout oligopeptide-1, a recombinant protein derived from rainbow trout, and sh-polypeptide-62, a synthetic human peptide designed to mimic Hepatocyte Growth Factor (HGF). It is proposed to support skin regeneration and overall cellular vitality.

Summary

Antioxidant Hair Conditioning Skin Protecting

Science

Mechanism of Action

The mechanism involves the combined action of its two primary components: sr-rainbow trout oligopeptide-1 and sh-polypeptide-62. Sh-polypeptide-62 acts as a biomimetic of Hepatocyte Growth Factor (HGF), a signaling protein known for its anti-aging and wound healing properties. Growth factors generally interact with keratinocyte receptors, thereby activating cellular pathways that promote accelerated new skin cell production, stimulate the synthesis of essential structural proteins such as collagen and elastin, and enhance overall skin texture. These actions collectively aim to improve skin repair, foster self-regeneration, support the formation of new blood vessels, reduce inflammatory responses, minimize scar appearance, and provide sustained moisturization.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Information regarding common dusting practices or specific dusting thresholds for this ingredient is not available in the provided research data.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

For optimal stability, products containing similar oligopeptide-polypeptide combinations should be stored within a temperature range of 2°C to 25°C (36°F to 77°F). Freezing and exposure to excessive heat above 40°C (104°F) should be avoided.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not yet evaluated the safety of this ingredient. It is important to note that products containing variations of 'sr-Rainbow Trout Oligopeptide-1 sh-Polypeptide' (including those similar to sh-Polypeptide-62) have been classified by the FDA as 'unapproved drug other,' meaning they have not been determined to be safe or effective, and their labeling has not received FDA approval.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While the ingredient exhibits a plausible mechanism for broad skin benefits, specific clinical efficacy for R-(S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-62) is not established, and similar compounds have been designated as 'unapproved drugs' by the FDA, warranting significant caution.

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