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R-OLIGOPEPTIDE-91 SH-POLYPEPTIDE-99.

Insufficient Data / SKIN CONDITIONING

R-Oligopeptide-91 SH-Polypeptide-99 is a sophisticated synthetic fusion peptide, meticulously engineered from amino acids, and likely produced via advanced fermentation. It functions as a potent skin conditioning and cell-communicating ingredient, designed to stimulate vital cellular processes within the skin.

Skin Conditioning Cell-communicating ingredient Cell Growth Stimulation Cell Proliferation Wound Healing Cell Differentiation Collagen Boosting Elastin Boosting Blood Vessel Stimulation Fibroblast Nutrition Cell Migration

Science

This single-chain fusion peptide operates by acting as a signaling molecule within the skin. Its constituent parts are theorized to promote critical cellular activities such as growth, proliferation, differentiation, and tissue healing. Notably, the SH-Polypeptide-9 component, a form of Vascular Endothelial Growth Factor, is instrumental in fostering new blood vessel formation, which ensures a robust nutrient supply to fibroblast cells, further supporting cell migration and wound repair. Concurrently, Oligopeptide-91 contributes to overall skin conditioning, enhancing the skin's functional integrity and appearance.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific stability data for R-Oligopeptide-91 SH-Polypeptide-99 is currently unavailable. As a class, peptides exhibit complex solubility and stability profiles that are highly dependent on their unique amino acid sequences and environmental conditions.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While this precise fusion peptide lacks individual review by the Cosmetic Ingredient Review (CIR), the CIR has broadly assessed categories of peptides, such as 'Soy Proteins and Peptides' and 'Ectodermal-Derived Proteins and Peptides', deeming them safe for cosmetic applications. No specific SCCS opinion or FDA cosmetic status has been established for this exact peptide, though peptones, which are mixtures of polypeptides and oligopeptides, are generally recognized as safe (GRAS) by the FDA for direct food use.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While its mechanistic potential suggests significant benefits for skin revitalization and repair, the current absence of specific clinical studies and comprehensive safety reviews for R-Oligopeptide-91 SH-Polypeptide-99 necessitates further dedicated research.


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