Science
Mechanism of Action
This single-chain fusion peptide operates by acting as a signaling molecule within the skin. Its constituent parts are theorized to promote critical cellular activities such as growth, proliferation, differentiation, and tissue healing. Notably, the SH-Polypeptide-9 component, a form of Vascular Endothelial Growth Factor, is instrumental in fostering new blood vessel formation, which ensures a robust nutrient supply to fibroblast cells, further supporting cell migration and wound repair. Concurrently, Oligopeptide-91 contributes to overall skin conditioning, enhancing the skin's functional integrity and appearance.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Specific stability data for R-Oligopeptide-91 SH-Polypeptide-99 is currently unavailable. As a class, peptides exhibit complex solubility and stability profiles that are highly dependent on their unique amino acid sequences and environmental conditions.
Safety
Safety Profile
While this precise fusion peptide lacks individual review by the Cosmetic Ingredient Review (CIR), the CIR has broadly assessed categories of peptides, such as 'Soy Proteins and Peptides' and 'Ectodermal-Derived Proteins and Peptides', deeming them safe for cosmetic applications. No specific SCCS opinion or FDA cosmetic status has been established for this exact peptide, though peptones, which are mixtures of polypeptides and oligopeptides, are generally recognized as safe (GRAS) by the FDA for direct food use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While its mechanistic potential suggests significant benefits for skin revitalization and repair, the current absence of specific clinical studies and comprehensive safety reviews for R-Oligopeptide-91 SH-Polypeptide-99 necessitates further dedicated research.
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