Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

R-(METHIONYL SH-POLYPEPTIDE-8 DECAPEPTIDE-40).

Insufficient Data / SKIN CONDITIONING, SKIN PROTECTING

R-(Methionyl Sh-Polypeptide-8 Decapeptide-40) is a peptide complex engineered to condition and protect the skin. It aims to enhance overall skin appearance, promoting a softer, smoother, and more hydrated feel, while also establishing a surface barrier against environmental stressors.

Skin Conditioning Skin Protecting

Science

This polypeptide functions as a skin conditioning agent by supporting improved hydration, texture, and suppleness, contributing to a visibly healthier and more youthful complexion. Additionally, it acts as a skin protecting agent, forming a barrier on the skin's surface to help shield against environmental aggressors. As with general peptides, it is theorized to signal the skin's endogenous repair mechanisms, stimulate regeneration in mature skin, reinforce structural integrity, and aid in the visible reduction of wrinkles, thereby enhancing both complexion and elasticity.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The ingredient may present aesthetic or stability challenges within a formulation.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Specific safety evaluations by CIR, SCCS, or FDA for R-(Methionyl Sh-Polypeptide-8 Decapeptide-40) are currently unavailable. While related peptides, such as Acetyl Hexapeptide-8 Amide, have been reviewed and deemed safe at concentrations up to 0.005% (with insufficient data for higher levels), the safety profile of this specific polypeptide remains largely unassessed at defined concentrations. Side effects from peptides are generally uncommon, but due to a medium irritancy rating, targeted patch testing is advised prior to widespread use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Insufficient Data

While demonstrating potential as a skin conditioner and protector, specific clinical data on the efficacy and safety concentrations of R-(Methionyl Sh-Polypeptide-8 Decapeptide-40) are currently insufficient for a definitive assessment.


Related

Finding similar ingredients…