Science
Mechanism of Action
This peptide primarily functions by moderating the skin's inflammatory cascade, specifically by reducing the production of interleukin-6 (IL-6), a pro-inflammatory cytokine known to accelerate the degradation of collagen and other structural proteins. By inhibiting IL-6, it protects the extracellular matrix from breakdown. QUINOYL TRIPEPTIDE-7 also stimulates the natural regeneration and production of collagen fibers, including collagen VII, and enhances laminin IV and V synthesis, crucial for skin architecture. Furthermore, it promotes phagocytosis, aiding in the clearance of cellular debris and bolstering natural defense. Its palmic acid attachment significantly enhances skin penetration.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
There is no indication in the provided research data that this ingredient is commonly 'dusted' or used at ineffective percentages in place of more potent actives. Typical effective use concentrations for the peptide content are reported to be very low, less than 10 ppm, which is standard for highly active peptides.
The Formula
Formulation
Stability
This peptide exhibits optimal stability within a pH range of 4.5 to 6.5. In its raw form, it is an odorless, white to off-white powder, and its incorporation into formulations does not alter their texture or appearance. The attached palmitic acid moiety imparts a lipophilic character, facilitating enhanced absorption into the skin.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed its safety for use in cosmetics at current concentrations. It is considered safe for topical application with a minimal risk of inducing irritation or sensitization, with typical peptide content use concentrations generally below 10 ppm.
Your Skin
Skin Compatibility
Our Assessment
Verdict
QUINOYL TRIPEPTIDE-7 is a valuable anti-aging peptide that significantly improves multiple signs of skin aging, including wrinkles and elasticity, while maintaining a low risk of irritation across all skin types.
Related
Similar Ingredients
Finding similar ingredients…