Science
Mechanism of Action
This extract functions via multiple pathways: its rich phenolic compounds and flavonoids provide robust antioxidant protection against free radicals and oxidative stress. It exhibits anti-inflammatory and anti-allergic properties. Specifically for acne, it demonstrates direct antibacterial action against Cutibacterium acnes, inhibiting its growth, biofilm formation, and lipase activity. Furthermore, it modulates key skin enzymes, inhibiting tyrosinase for potential skin brightening and elastase to support skin elasticity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 At a concentration of 0.5 mg/disc, it produced a 12.63 mm inhibition zone against Cutibacterium acnes, indicating anti-acne potential (in vitro).
- 02 At 1000 μg/mL, it significantly inhibited Cutibacterium acnes biofilm formation by up to 86.19% (in vitro).
- 03 Concentrations of 200-400 μg/mL inhibited advanced glycation end-product (AGE) formation (in vitro).
- 04 At 10-20 μg/mL, it inhibited AGE-collagen cross-linking (in vitro).
- 05 Demonstrated strong antioxidant activity and inhibitory effects on tyrosinase and elastase (in vitro).
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Comprehensive safety evaluations by major regulatory bodies (CIR, SCCS, FDA) for cosmetic use are not available. General studies mention a possibly low level of cytotoxicity in a review of its bioactive compounds.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Quercus Salicina Leaf Extract displays broad in vitro potential for addressing acne, aging, and oxidative stress; however, further in vivo studies and regulatory safety data are essential for a definitive assessment in precision skincare.
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References
Sources