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Moumoujus

QUERCUS SALICINA EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Quercus Salicina Extract, derived from the Japanese willow oak, is a multifaceted botanical ingredient engineered to address prevalent skin concerns. It leverages potent antimicrobial, antioxidant, and anti-inflammatory properties to effectively combat acne, mitigate oxidative damage, and diminish visible signs of aging.

Summary

Antioxidant Anti-inflammatory Antibacterial Anti-acne Skin Brightening Anti-aging Biofilm inhibition Lipase inhibition

Science

Mechanism of Action

This extract is notably rich in phenolic compounds and flavonoids, which are instrumental in its robust antioxidant capacity, actively scavenging free radicals and reactive oxygen species to prevent cellular oxidative stress. Its efficacy extends to significant antibacterial and antimicrobial actions, particularly against Cutibacterium acnes, where it curtails bacterial proliferation, inhibits biofilm formation, and reduces lipase activity. Moreover, Quercus Salicina Extract exhibits anti-inflammatory effects and demonstrates inhibitory activity against tyrosinase, contributing to skin brightening, and elastase, supporting dermal elasticity and anti-aging interventions. Preliminary data also suggest potential anti-allergic attributes.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibitory effect on Cutibacterium acnes growth (in vitro).
  2. 02 Strong inhibitory effect on C. acnes biofilm formation (up to 86.19%) (in vitro).
  3. 03 Highest lipase inhibition (93.72%) from C. acnes (in vitro).
  4. 04 Exhibited DPPH free radical scavenging activities ranging from 33.9% (10 μg/mL) to 91.6% (500 μg/mL) (in vitro).
  5. 05 Concentration-dependent reduction of Bax expression and reversal of increased Bcl-2, procaspase-9, and caspase-3 expressions in cadmium-treated HK-2 cells, indicating anti-apoptotic effects (in vitro).

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

A cream containing 0.25% of an ethyl acetate fraction of Quercus Salicina Extract demonstrated stability in pH, viscosity, color, and odor over a 12-week period when stored at various temperatures (4-45°C) and under sunlight. Its diverse phenolic compounds allow for both water-soluble (phenolic acids, flavonoids) and water-insoluble (condensed tannins) forms.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments by CIR, SCCS, or FDA for cosmetic use were found. However, studies mention 'possibly low-level of cytotoxicity' and its traditional use in folk medicine for dermatitis, implying a good safety profile and low irritancy.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Quercus Salicina Extract is a valuable botanical ingredient offering a broad spectrum of benefits, particularly effective in managing acne, oxidative stress, and signs of aging, with a promising safety profile based on current in-vitro data and traditional use.

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