Science
Mechanism of Action
This extract functions primarily as an antioxidant by inhibiting reactions promoted by oxygen and preventing ingredient deterioration through radical scavenging and iron chelation. Its richness in polyphenols, including flavonoids, tannins, and proanthocyanidins, underpins its protective effects against oxidative stress. Extracts from *Quercus* species generally exhibit anti-inflammatory and antimicrobial properties. The tannin content may also act as a tyrosinase inhibitor, influencing skin pigmentation, while traditional uses suggest astringent and wound-healing benefits.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An extract demonstrated significant free radical scavenging and iron chelating activities. A patch test in 19 volunteers indicated it was safe for topical application, suggesting low irritation potential.
- 02 Butanol extracts showed activity against *Staphylococcus aureus* biofilm formation, suggesting antimicrobial benefits.
- 03 Leaves exhibited superior antioxidant characteristics over other plant parts in various antiradical power assays (DPPH•, •NO, O2•− radicals, FRAP, PRAC), reinforcing the extract's broad-spectrum antioxidant capacity.
Transparency
Dusting Analysis
There is no indication this ingredient is commonly used at sub-efficacious concentrations for marketing purposes.
The Formula
Formulation
Safety
Safety Profile
While specific CIR, SCCS, or FDA safety status for QUERCUS PUBESCENS LEAF/STEM EXTRACT is not yet established, an in-vivo patch test on an extract from a related species, *Quercus robur*, in 19 volunteers indicated safety for topical use. This suggests a low potential for irritation or sensitization.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Quercus pubescens Leaf/Stem Extract is a valuable ingredient due to its strong antioxidant profile and potential for soothing and antimicrobial benefits, though further direct clinical research on this specific species in human skin is warranted.
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