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Moumoujus

QUERCUS ACUTISSIMA FRUIT EXTRACT.

Valuable CAS - / ASTRINGENT

Quercus Acutissima Fruit Extract, derived from the Japanese evergreen oak, is a multifaceted botanical ingredient celebrated for its ability to tighten and refine the skin. It acts as a potent antioxidant and anti-inflammatory agent, while also offering significant anti-photoaging benefits against environmental damage.

Summary

Astringent Antioxidant Skin-Conditioning Anti-inflammatory Anti-photoaging Antimicrobial

Science

Mechanism of Action

This extract operates through several key pathways to enhance skin health. As an astringent, it helps to visibly tighten the skin, minimizing the appearance of pores and assisting in the regulation of sebum production, which can reduce breakouts. Its powerful antioxidant properties enable it to neutralize harmful free radicals, thereby mitigating oxidative stress induced by environmental aggressors such as UV radiation and pollutants. The extract also demonstrates anti-inflammatory effects by effectively suppressing nitric oxide production and the expression of iNOS, and inhibiting various inflammatory proteins implicated in conditions like acne. Furthermore, it exhibits anti-photoaging capabilities by promoting collagen synthesis and inhibiting matrix metalloproteinase-1 (MMP-1) via the ERK/AP-1 signaling pathway, which actively prevents UVB-induced skin degradation. Beyond these, it functions as a skin conditioning agent, forming a protective barrier to lock in moisture, and possesses antimicrobial properties that safeguard both the formulation and skin against microbial proliferation.

Research

Clinical Evidence

Medium confidence
Effective range 25 µg/mL–50 µg/mL%
Optimal

N/A

Key findings

  1. 01 In laboratory settings, concentrations as low as 25 µg/mL of a Quercus Fructus extract (including Quercus acutissima) were shown to significantly suppress nitric oxide production and iNOS expression in LPS-stimulated Raw 264.7 cells, indicating anti-inflammatory action without cytotoxicity.
  2. 02 A higher antioxidant activity was observed for Quercus acutissima Carruth extract at 50 µg/mL.
  3. 03 An aqueous extract, at an unspecified concentration, effectively countered UVB-induced cell toxicity, reduced intracellular reactive oxygen species (ROS) generation, and prevented collagen degradation by inhibiting MMP-1 expression. It also demonstrated anti-photoaging effects by modulating the ERK and AP-1 signaling pathways in human keratinocytes.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This extract is typically prepared as an aqueous solution. For enhanced extraction of key beneficial compounds like gallic acid, an 80% ethanol solvent has also proven effective.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Quercus Acutissima Fruit Extract is generally considered safe for topical application in cosmetic formulations. However, formal safety reviews by expert panels such as the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) have not been conducted specifically for this ingredient. Specific data regarding topical use during pregnancy and breastfeeding is insufficient, and professional medical advice is recommended for these individuals.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Quercus Acutissima Fruit Extract is a valuable botanical ingredient offering a broad spectrum of benefits including astringency, potent antioxidant and anti-inflammatory effects, and clinically observed anti-photoaging properties, making it suitable for diverse skincare formulations, particularly for normal, oily, and dry skin.

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