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Moumoujus

QUERCETAGETIN.

Insufficient Data CAS 90-18-6 / SKIN PROTECTING

Quercetagetin is a flavonoid demonstrating potent anti-inflammatory and antioxidant capabilities. It operates by modulating specific inflammatory signaling pathways and directly neutralizing reactive oxygen species within skin cells, indicating potential for targeted skin barrier support.

Summary

Anti-inflammatory Antioxidant

Science

Mechanism of Action

Quercetagetin acts as an anti-inflammatory agent by specifically inhibiting the STAT1 signaling pathway, which is integral to various inflammatory responses. In vitro studies utilizing IFN-γ and TNF-α-stimulated HaCaT human keratinocytes have shown its superior efficacy in reducing both protein and mRNA expression of TARC and MDC chemokines when compared to other flavonoids. Additionally, Quercetagetin functions as an antioxidant, effectively scavenging reactive oxygen species (ROS) and modulating critical signaling pathways linked to oxidative stress.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by prominent regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the FDA have been identified for Quercetagetin in cosmetic applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Quercetagetin exhibits promising in vitro anti-inflammatory and antioxidant properties; however, a comprehensive evaluation requires further clinical efficacy, safety, and formulation data.

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